SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Skogh Thomas)
 

Sökning: WFRF:(Skogh Thomas) > Zeffer E > A Population-based ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00008148naa a2200793 4500
001oai:DiVA.org:liu-72019
003SwePub
008111111s2011 | |||||||||||000 ||eng|
009oai:DiVA.org:umu-45884
009oai:lup.lub.lu.se:8c6d3043-dd4f-4aa2-8535-d7c325f678f5
009oai:prod.swepub.kib.ki.se:123467520
009oai:DiVA.org:uu-161434
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-720192 URI
0247 a https://doi.org/10.1111/j.1365-3083.2011.02610.x2 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-458842 URI
0247 a https://lup.lub.lu.se/record/21514652 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1234675202 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1614342 URI
040 a (SwePub)liud (SwePub)umud (SwePub)lud (SwePub)kid (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Salomonsson, S.u Karolinska Institutet,Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden,Department of Rheumatology, Umeå University, Sweden,Department of Women and Child Health, Karolinska Institutet, Stockholm, Sweden4 aut
2451 0a A Population-based Investigation of the Autoantibody Profile in Mothers of Children with Atrioventricular Block
264 c 2011-10-05
264 1a Oxford :b Blackwell Publishing,c 2011
338 a electronic2 rdacarrier
500 a Funding Agencies|KIRCNET (Karolinska Institutet Circulation and Respiratory Research Network)||Magn Bergvalls Foundation||Jerringfoundation||Stiftelsen Samariten||Karolinska Institute||Royal Swedish Academy of Sciences||Swedish Research Council||Goran Gustafsson Foundation||Torsten and Ragnar Soderberg Foundation||King Gustaf the V:th 80-year foundation||Swedish Foundation for Strategic Research||Heart-Lung Foundation||Swedish Rheumatism Association||
520 a The objective of the study was to investigate the antigen specificity and occurrence of individual autoantibodies in mothers of children diagnosed with atrioventricular (AV) block in a nation-wide setting. Patients with AV block detected before 15 years of age were identified using national quality registries as well as a network of pediatric and adult cardiologists and rheumatologists at the six university hospitals in Sweden. Patients with gross heart malformations, surgically or infectiously induced blocks were excluded. Blood samples were obtained from the mothers and maternal autoantibody profile, including the occurrence of antibodies against Ro52, Ro60, La, SmB, SmD, RNP-70k, RNP-A, RNP-C, CENP-C, Scl-70, Jo-1, ribosomal RNP and histones was investigated in 193 mothers of children with AV block by immunoblotting and ELISA. Autoantibody reactivity was detected in 48% (93/193) of the mothers of children with AV block. In autoantibody-positive mothers, the vast majority, 95% (88/93), had antibodies against Ro52, while 63% (59/93) had autoantibodies to Ro60 and 58% (54/93) had autoantibodies to La. In addition, 13% (12/93) of the autoantibody-positive mothers had antibodies to other investigated antigens besides Ro52, Ro60 and La, and of these anti-histone antibodies were most commonly represented, detected in 8% (7/93) of the mothers. In conclusion, this Swedish population-based study confirms that maternal autoantibodies may associate with heart block in the child. Further, our data demonstrate a dominant role of Ro52 antibodies in association with AV block.
650 7a NATURVETENSKAPx Biologix Immunologi0 (SwePub)106052 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Immunology0 (SwePub)106052 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng
653 a MEDICINE
653 a MEDICIN
7001 a Dzikaite, V.u Karolinska Institutet,Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Zeffer, E.u Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Eliasson, H.u Karolinska Institutet,Department of Women and Child Health, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Ambrosi, A.u Karolinska Institutet,Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden,Department of Clinical Sciences, Paediatrics, Umeå University, Sweden,Uppsala University4 aut
7001 a Bergman, G.u Karolinska Institutet,Department of Women and Child Health, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Fernlund, E.u Skåne University Hospital, Malmö,Department of Pediatric Cardiology, Skane University Hospital, Lund, Sweden4 aut
7001 a Theander, Elkeu Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine,Rheumatology Department, Skåne University Hospital, Malmö, Sweden4 aut0 (Swepub:lu)medf-eth
7001 a Öhman, Annika,d 1971-u Uppsala universitet,Institutionen för kvinnors och barns hälsa,Perinatal, neonatal och barnkardiologisk forskning/Jonzon4 aut0 (Swepub:uu)annoh601
7001 a Rydberg, Annikau Umeå universitet,Pediatrik4 aut0 (Swepub:umu)anry0014
7001 a Skogh, Thomasu Östergötlands Läns Landsting,Linköpings universitet,Reumatologi,Hälsouniversitetet,Reumatologiska kliniken i Östergötland,Rheumatology/AIR, Clinical and Experimental Medicine, Linköping University, Sweden4 aut0 (Swepub:liu)thosk00
7001 a Wållberg-Jonsson, Solveigu Umeå universitet,Reumatologi4 aut0 (Swepub:umu)sowa0001
7001 a Elfving, Å.u Karolinska Institutet, Stockholm4 aut
7001 a Fored, M.u Karolinska Institutet,Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Ekbom, A.u Karolinska Institutet, Stockholm4 aut
7001 a Lundström, U.u Department of Pediatric Cardiology, The Queen Silvia Children′s Hospital, Sahlgrenska University Hospital, Göteborg, Sweden4 aut
7001 a Mellander, M.u Karolinska Institutet,Department of Pediatric Cardiology, The Queen Silvia Children′s Hospital, Sahlgrenska University Hospital, Göteborg, Sweden,Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Winqvist, O.u Karolinska Institutet,Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Sonesson, S.-E.u Karolinska Institutet, Stockholm4 aut
7001 a Gadler, F.u Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 aut
7001 a Jonzon, Anders,d 1948-u Uppsala universitet,Institutionen för kvinnors och barns hälsa,Perinatal, neonatal och barnkardiologisk forskning/Jonzon4 aut0 (Swepub:uu)andersjz
7001 a Wahren-Herlenius, M.u Karolinska Institutet, Stockholm4 aut
7102 a Karolinska Institutetb Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden4 org
7730 t Scandinavian Journal of Immunologyd Oxford : Blackwell Publishingg 74:5, s. 511-517q 74:5<511-517x 0300-9475x 1365-3083
8564 u https://liu.diva-portal.org/smash/get/diva2:456025/FULLTEXT02.pdfx primaryx Raw objecty fulltext:preprint
8564 u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-3083.2011.02610.x
8564 u http://www.ncbi.nlm.nih.gov/pubmed/21815910?dopt=Abstracty FULLTEXT
8564 u http://dx.doi.org/10.1111/j.1365-3083.2011.02610.xy FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-72019
8564 8u https://doi.org/10.1111/j.1365-3083.2011.02610.x
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-45884
8564 8u https://lup.lub.lu.se/record/2151465
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:123467520
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-161434

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy