WFRF:(Steineck Gunnar)
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04301naa a2200397 4500 | |
| 001 | oai:gup.ub.gu.se/169247 | |
| 003 | SwePub | |
| 008 | 240528s2013 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:oru-56751 | |
| 009 | oai:prod.swepub.kib.ki.se:126547828 | |
| 024 | 7 | a https://gup.ub.gu.se/publication/1692472 URI |
| 024 | 7 | a https://doi.org/10.3109/0284186X.2012.7241792 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-567512 URI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1265478282 URI |
| 040 | a (SwePub)gud (SwePub)orud (SwePub)ki | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Sorbe, Bengtu Region Örebro län,Dept Oncol4 aut0 (Swepub:oru)bse |
| 245 | 1 0 | a A population-based series of uterine carcinosarcomas with long-term follow-up. |
| 264 | 1 | b Informa Healthcare,c 2013 |
| 520 | a Background. Carcinosarcomas are a highly malignant type of endometrial carcinomas where extra uterine spread and recurrences are frequent. There is no consensus regarding the best treatment of this group of malignancies. Material and methods. In a complete geographic series of 322 cases of primary uterine carcinosarcomas prophylactic pelvic irradiation and/or chemotherapy was used as postoperative treatment in the majority of the cases. Vaginal brachytherapy was also added as a boost. The primary surgery was extended hysterectomy in 23 cases (10%), and simple hysterectomy in 220 cases (90%). In 46 cases (14%) no major surgery was possible. Results. In the complete series 123 recurrences (38%) were recorded. Locoregional recurrences (11%) and distant recurrences (28%) were most frequent. Type and extent of surgery was not associated with the risk of tumor recurrence. Extended surgery did not reduce the risk of local and regional recurrences. In the complete series, the five-year overall survival rate was 30% and the recurrence-free survival (RFS) rate was 27%. The five-year pelvic disease control was 82% in stage I, 68% in stage II, and 76% for more advanced stages. The five-year locoregional RFS rate was 63% for patients treated with surgery alone, 68% after addition of adjuvant chemotherapy, 86% after adjuvant radiotherapy, and 95% after combined chemotherapy and radiotherapy. Conclusion. Radiotherapy seems to be the most important constituent of the adjuvant therapy. Serious late tissue reactions, requiring surgery, from the bladder and intestine occurred in 2.5% of the irradiated cases. The death of three patients could be related to radiotherapy and of four patients due to the cytotoxic treatment. This population-based series may serve as a baseline for improvements by, e.g. standard care programs and referral to a few specialist centers for this rare and serious disease. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Urologi och njurmedicin0 (SwePub)302142 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Urology and Nephrology0 (SwePub)302142 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 700 | 1 | a Paulsson, Gunnaru Dept Gynecol & Obstet, Cent Hosp Skövde, Skövde, Sweden4 aut |
| 700 | 1 | a Andersson, Solveigu Dept Gynecol & Obstet, Mälarsjukhuset, Eskilstuna, Sweden4 aut |
| 700 | 1 | a Steineck, Gunnar,d 1952u Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology,Dept Clin Canc Epidemiol,Inst Clin Sci,Dept Oncol, Sahlgrenska Univ Hosp, Sahlgrenska Acad, Univ Gothenburg, Gothenburg, Sweden4 aut0 (Swepub:gu)xstegu |
| 710 | 2 | a Region Örebro länb Dept Oncol4 org |
| 773 | 0 | t Acta oncologica (Stockholm, Sweden)d : Informa Healthcareg 52:4, s. 759-66q 52:4<759-66x 1651-226Xx 0284-186X |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/169247 |
| 856 | 4 8 | u https://doi.org/10.3109/0284186X.2012.724179 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-56751 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:126547828 |
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