WFRF:(Stoppia L)
Sökning: WFRF:(Stoppia L) > (2011) > A protective geneti...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02907naa a2200361 4500 | |
| 001 | oai:prod.swepub.kib.ki.se:123617447 | |
| 003 | SwePub | |
| 008 | 240913s2011 | |||||||||||000 ||eng| | |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1236174472 URI |
| 024 | 7 | a https://doi.org/10.1016/j.eurpsy.2011.04.0082 DOI |
| 040 | a (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Carli, Vu Karolinska Institutet4 aut |
| 245 | 1 0 | a A protective genetic variant for adverse environments? The role of childhood traumas and serotonin transporter gene on resilience and depressive severity in a high-risk population |
| 264 | c 2020-04-16 | |
| 264 | 1 | b Cambridge University Press (CUP),c 2011 |
| 520 | a Genetic aspects may influence the effect of early adverse events on psychological well being in adulthood. In particular, a common polymorphism within the serotonin transporter gene (5-HTTLPR short/long) has been associated to the risk for stress-induced psychopathology. In the present study we investigated the role of childhood traumas and 5-HTTLPR on measures of psychological resilience and depression in a sample of individuals at a high risk for psychological distress (763 male prisoners). The 5-HTTLPR genotype did not influence resilience and depressive severity. However, a significant interaction was observed between 5-HTTLPR and childhood traumas on both resilience and depressive severity. In particular, among subjects exposed to severe childhood trauma only, the long-allele was associated to lower resilience scores and increased current depressive severity as compared to short/short homozygous. Sex specific effects, difference in type and duration of stressors and the specific composition of the sample may explain discrepancy with many studies reporting the short-allele as a vulnerability factor for reactivity to stress. We here speculated that in males the long-allele may confer lower resilience and therefore higher vulnerability for depressive symptoms in subjects exposed to early stress and currently living in stressful environments. | |
| 700 | 1 | a Mandelli, L4 aut |
| 700 | 1 | a Zaninotto, L4 aut |
| 700 | 1 | a Roy, A4 aut |
| 700 | 1 | a Recchia, L4 aut |
| 700 | 1 | a Stoppia, L4 aut |
| 700 | 1 | a Gatta, V4 aut |
| 700 | 1 | a Sarchiapone, M4 aut |
| 700 | 1 | a Serretti, A4 aut |
| 710 | 2 | a Karolinska Institutet4 org |
| 773 | 0 | t European psychiatry : the journal of the Association of European Psychiatristsd : Cambridge University Press (CUP)g 26:8, s. 471-478q 26:8<471-478x 1778-3585 |
| 773 | 0 | t European Psychiatryd : Cambridge University Press (CUP)g 26:8, s. 471-478q 26:8<471-478x 0924-9338 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:123617447 |
| 856 | 4 8 | u https://doi.org/10.1016/j.eurpsy.2011.04.008 |
Hitta via bibliotek
- European psychiatry : the journal of the Association of European Psychiatrists (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Carli, V
- Mandelli, L
- Zaninotto, L
- Roy, A
- Recchia, L
- Stoppia, L
- visa fler...
- Gatta, V
- Sarchiapone, M
- Serretti, A
- visa färre...
- Artiklar i publikationen
- European psychia ...
- European Psychia ...
- Av lärosätet
- Karolinska Institutet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
