Sökning: WFRF:(Streptlg Study Group) > Intravenous immunog...
Fältnamn | Indikatorer | Metadata |
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000 | 03953naa a2200541 4500 | |
001 | oai:DiVA.org:liu-26445 | |
003 | SwePub | |
008 | 091008s2003 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:33f28498-a21c-4860-977c-af8157750891 | |
009 | oai:prod.swepub.kib.ki.se:1928004 | |
009 | oai:DiVA.org:uu-65595 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-264452 URI |
024 | 7 | a https://doi.org/10.1086/3766302 DOI |
024 | 7 | a https://lup.lub.lu.se/record/9001172 URI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19280042 URI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-655952 URI |
040 | a (SwePub)liud (SwePub)lud (SwePub)kid (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Darenberg, Ju Karolinska Institutet4 aut |
245 | 1 0 | a Intravenous immunoglobulin G therapy in streptococcal toxic shock syndrome :b A European randomized, double-blind, placebo-controlled trial |
264 | 1 | b Oxford University Press (OUP),c 2003 |
338 | a print2 rdacarrier | |
520 | a The efficacy and safety of high-dose intravenous polyspecific immunoglobulin G (IVIG) as adjunctive therapy in streptococcal toxic shock syndrome (STSS) were evaluated in a multicenter, randomized, double-blind, placebo-controlled trial. The trial was prematurely terminated because of slow patient recruitment, and results were obtained from 21 enrolled patients (10 IVIG recipients and 11 placebo recipients). The primary end point was mortality at 28 days, and a 3.6-fold higher mortality rate was found in the placebo group. A significant decrease in the sepsis-related organ failure assessment score at days 2 (P = .02) and 3 (P = .04) was noted in the IVIG group. Furthermore, a significant increase in plasma neutralizing activity against superantigens expressed by autologous isolates was noted in the IVIG group after treatment (P = .03). Although statistical significance was not reached in the primary end point, the trial provides further support for IVIG as an efficacious adjunctive therapy in STSS. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Ihendyane, N4 aut |
700 | 1 | a Sjölin, Ju Uppsala universitet,Institutionen för medicinska vetenskaper,Infektion, Göran Friman4 aut |
700 | 1 | a Aufwerber, E4 aut |
700 | 1 | a Haidl, Svenu Lund University,Lunds universitet,Enheten för infektionssjukdomar,Forskargrupper vid Lunds universitet,Infectious Diseases Research Unit,Lund University Research Groups4 aut0 (Swepub:lu)inf-sha |
700 | 1 | a Follin, Per,d 1953-u Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Infektionsmedicin,Infektionskliniken i Östergötland4 aut0 (Swepub:liu)perfo43 |
700 | 1 | a Andersson, Ju Karolinska Institutet4 aut |
700 | 1 | a Norrby-Teglund, Au Karolinska Institutet4 aut |
700 | 1 | a Streptlg Study, Group4 aut |
710 | 2 | a Karolinska Institutetb Institutionen för medicinska vetenskaper4 org |
773 | 0 | t Clinical Infectious Diseasesd : Oxford University Press (OUP)g 37, s. 333-q 37:3<333-340x 1058-4838x 1537-6591 |
773 | 0 | t Clin Infect Disd : Oxford University Press (OUP)g 37, s. 333-q 37<333- |
856 | 4 | u https://academic.oup.com/cid/article-pdf/37/3/333/1195857/37-3-333.pdf |
856 | 4 | u http://dx.doi.org/10.1086/376630y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-26445 |
856 | 4 8 | u https://doi.org/10.1086/376630 |
856 | 4 8 | u https://lup.lub.lu.se/record/900117 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1928004 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-65595 |
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