WFRF:(Sullivan Patrick F)
Sökning: WFRF:(Sullivan Patrick F) > (2005-2009) > Common polygenic va...
- 1 av 12
- Föregående post
- Nästa post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04819naa a2201213 4500 | |
| 001 | oai:DiVA.org:uu-128329 | |
| 003 | SwePub | |
| 008 | 100720s2009 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:119170677 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1283292 URI |
| 024 | 7 | a https://doi.org/10.1038/nature081852 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1191706772 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Purcell, Shaun M.4 aut |
| 245 | 1 0 | a Common polygenic variation contributes to risk of schizophrenia and bipolar disorder |
| 264 | c 2009-07-01 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2009 |
| 338 | a print2 rdacarrier | |
| 520 | a Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80%(1,2). We performed a genome-wide association study of 3,322 European individuals with schizophrenia and 3,587 controls. Here we show, using two analytic approaches, the extent to which common genetic variation underlies the risk of schizophrenia. First, we implicate the major histocompatibility complex. Second, we provide molecular genetic evidence for a substantial polygenic component to the risk of schizophrenia involving thousands of common alleles of very small effect. We show that this component also contributes to the risk of bipolar disorder, but not to several non-psychiatric diseases. | |
| 653 | a MEDICINE | |
| 653 | a MEDICIN | |
| 700 | 1 | a Wray, R4 aut |
| 700 | 1 | a Stone, L4 aut |
| 700 | 1 | a Visscher, M4 aut |
| 700 | 1 | a O'Donovan, C4 aut |
| 700 | 1 | a Sullivan, F4 aut |
| 700 | 1 | a Sklar, Pamela4 aut |
| 700 | 1 | a Ruderfer, M4 aut |
| 700 | 1 | a McQuillin, Andrew4 aut |
| 700 | 1 | a Morris, W4 aut |
| 700 | 1 | a O'Dushlaine, T4 aut |
| 700 | 1 | a Corvin, Aiden4 aut |
| 700 | 1 | a Holmans, A4 aut |
| 700 | 1 | a Macgregor, Stuart4 aut |
| 700 | 1 | a Gurling, Hugh4 aut |
| 700 | 1 | a Blackwood, R4 aut |
| 700 | 1 | a Craddock, J4 aut |
| 700 | 1 | a Gill, Michael4 aut |
| 700 | 1 | a Hultman, Christina M.u Karolinska Institutet,Uppsala universitet,Institutionen för neurovetenskap4 aut |
| 700 | 1 | a Kirov, K4 aut |
| 700 | 1 | a Lichtenstein, Paulu Karolinska Institutet4 aut |
| 700 | 1 | a Muir, J4 aut |
| 700 | 1 | a Owen, J4 aut |
| 700 | 1 | a Pato, N4 aut |
| 700 | 1 | a Scolnick, M4 aut |
| 700 | 1 | a St Clair, David4 aut |
| 700 | 1 | a Williams, M4 aut |
| 700 | 1 | a Georgieva, Lyudmila4 aut |
| 700 | 1 | a Nikolov, Ivan4 aut |
| 700 | 1 | a Norton, N4 aut |
| 700 | 1 | a Williams, H4 aut |
| 700 | 1 | a Toncheva, Draga4 aut |
| 700 | 1 | a Milanova, Vihra4 aut |
| 700 | 1 | a Thelander, F4 aut |
| 700 | 1 | a Sullivan, Patrick4 aut |
| 700 | 1 | a Kenny, Elaine4 aut |
| 700 | 1 | a Quinn, M4 aut |
| 700 | 1 | a Choudhury, Khalid4 aut |
| 700 | 1 | a Datta, Susmita4 aut |
| 700 | 1 | a Pimm, Jonathan4 aut |
| 700 | 1 | a Thirumalai, Srinivasa4 aut |
| 700 | 1 | a Puri, Vinay4 aut |
| 700 | 1 | a Krasucki, Robert4 aut |
| 700 | 1 | a Lawrence, Jacob4 aut |
| 700 | 1 | a Quested, Digby4 aut |
| 700 | 1 | a Bass, Nicholas4 aut |
| 700 | 1 | a Crombie, Caroline4 aut |
| 700 | 1 | a Fraser, Gillian4 aut |
| 700 | 1 | a Kuan, Leh4 aut |
| 700 | 1 | a Walker, Nicholas4 aut |
| 700 | 1 | a McGhee, A4 aut |
| 700 | 1 | a Pickard, Ben4 aut |
| 700 | 1 | a Malloy, Pat4 aut |
| 700 | 1 | a Maclean, W4 aut |
| 700 | 1 | a Van Beck, Margaret4 aut |
| 700 | 1 | a Pato, T4 aut |
| 700 | 1 | a Medeiros, Helena4 aut |
| 700 | 1 | a Middleton, Frank4 aut |
| 700 | 1 | a Carvalho, Celia4 aut |
| 700 | 1 | a Morley, Christopher4 aut |
| 700 | 1 | a Fanous, Ayman4 aut |
| 700 | 1 | a Conti, David4 aut |
| 700 | 1 | a Knowles, A4 aut |
| 700 | 1 | a Ferreira, Paz4 aut |
| 700 | 1 | a Macedo, Antonio4 aut |
| 700 | 1 | a Azevedo, Helena4 aut |
| 700 | 1 | a Kirby, N4 aut |
| 700 | 1 | a Ferreira, R4 aut |
| 700 | 1 | a Daly, J4 aut |
| 700 | 1 | a Chambert, Kimberly4 aut |
| 700 | 1 | a Kuruvilla, Finny4 aut |
| 700 | 1 | a Gabriel, B4 aut |
| 700 | 1 | a Ardlie, Kristin4 aut |
| 700 | 1 | a Moran, Jennifer L.4 aut |
| 710 | 2 | a Uppsala universitetb Institutionen för neurovetenskap4 org |
| 773 | 0 | t Natured : Springer Science and Business Media LLCg 460:7256, s. 748-752q 460:7256<748-752x 0028-0836x 1476-4687 |
| 856 | 4 | u https://europepmc.org/articles/pmc3912837?pdf=render |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-128329 |
| 856 | 4 8 | u https://doi.org/10.1038/nature08185 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:119170677 |
- 1 av 12
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Purcell, Shaun M ...
- Wray, R
- Stone, L
- Visscher, M
- O'Donovan, C
- Sullivan, F
- visa fler...
- Sklar, Pamela
- Ruderfer, M
- McQuillin, Andre ...
- Morris, W
- O'Dushlaine, T
- Corvin, Aiden
- Holmans, A
- Macgregor, Stuar ...
- Gurling, Hugh
- Blackwood, R
- Craddock, J
- Gill, Michael
- Hultman, Christi ...
- Kirov, K
- Lichtenstein, Pa ...
- Muir, J
- Owen, J
- Pato, N
- Scolnick, M
- St Clair, David
- Williams, M
- Georgieva, Lyudm ...
- Nikolov, Ivan
- Norton, N
- Williams, H
- Toncheva, Draga
- Milanova, Vihra
- Thelander, F
- Sullivan, Patric ...
- Kenny, Elaine
- Quinn, M
- Choudhury, Khali ...
- Datta, Susmita
- Pimm, Jonathan
- Thirumalai, Srin ...
- Puri, Vinay
- Krasucki, Robert
- Lawrence, Jacob
- Quested, Digby
- Bass, Nicholas
- Crombie, Carolin ...
- Fraser, Gillian
- Kuan, Leh
- Walker, Nicholas
- McGhee, A
- Pickard, Ben
- Malloy, Pat
- Maclean, W
- Van Beck, Margar ...
- Pato, T
- Medeiros, Helena
- Middleton, Frank
- Carvalho, Celia
- Morley, Christop ...
- Fanous, Ayman
- Conti, David
- Knowles, A
- Ferreira, Paz
- Macedo, Antonio
- Azevedo, Helena
- Kirby, N
- Ferreira, R
- Daly, J
- Chambert, Kimber ...
- Kuruvilla, Finny
- Gabriel, B
- Ardlie, Kristin
- Moran, Jennifer ...
- visa färre...
- Artiklar i publikationen
- Nature
- Av lärosätet
- Uppsala universitet
- Karolinska Institutet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
