Sökning: WFRF:(Thanos D.) > LifeTime and improv...
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000 | 09340naa a2202593 4500 | |
001 | oai:DiVA.org:kth-284813 | |
003 | SwePub | |
008 | 201117s2020 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:145092804 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-2848132 URI |
024 | 7 | a https://doi.org/10.1038/s41586-020-2715-92 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1450928042 URI |
040 | a (SwePub)kthd (SwePub)ki | |
041 | a engb eng | |
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100 | 1 | a Rajewsky, N.4 aut |
245 | 1 0 | a LifeTime and improving European healthcare through cell-based interceptive medicine |
264 | c 2020-09-07 | |
264 | 1 | b Springer Nature,c 2020 |
338 | a print2 rdacarrier | |
500 | a QC 20201117Correction in: Nature, Volume 587, Issue 7834, Pages 377 - 386, 19 November 2020. DOI: 10.1038/s41586-021-03287-8, Scopus ID: 2-s2.0-85102698588 | |
520 | a LifeTime aims to track, understand and target human cells during the onset and progression of complex diseases and their response to therapy at single-cell resolution. This mission will be implemented through the development and integration of single-cell multi-omics and imaging, artificial intelligence and patient-derived experimental disease models during progression from health to disease. Analysis of such large molecular and clinical datasets will discover molecular mechanisms, create predictive computational models of disease progression, and reveal new drug targets and therapies. Timely detection and interception of disease embedded in an ethical and patient-centered vision will be achieved through interactions across academia, hospitals, patient-associations, health data management systems and industry. Applying this strategy to key medical challenges in cancer, neurological, infectious, chronic inflammatory and cardiovascular diseases at the single-cell level will usher in cell-based interceptive medicine in Europe over the next decade. | |
650 | 7 | a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Bioinformatik och systembiologi0 (SwePub)106102 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Bioinformatics and Systems Biology0 (SwePub)106102 hsv//eng |
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700 | 1 | a Linnarsson, S.u Karolinska Institutet4 aut |
700 | 1 | a Marine, J. -C4 aut |
700 | 1 | a Marioni, J.4 aut |
700 | 1 | a Marti-Renom, M. A.4 aut |
700 | 1 | a Netea, M. G.4 aut |
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700 | 1 | a Thanos, D.4 aut |
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700 | 1 | a Torres-Padilla, M. -E4 aut |
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700 | 1 | a Herland, Annau KTH,Mikro- och nanosystemteknik4 aut0 (Swepub:kth)u1koqi31 |
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700 | 1 | a Marelli, L.4 aut |
700 | 1 | a Matser, V.4 aut |
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700 | 1 | a Saliba, A. -E4 aut |
700 | 1 | a Sanchez-Valle, R.4 aut |
700 | 1 | a Santosuosso, A.4 aut |
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700 | 1 | a Scheltema, R. A.4 aut |
700 | 1 | a Scheltens, P.4 aut |
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700 | 1 | a Van de Poel, I.4 aut |
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700 | 1 | a Van Paesschen, W.4 aut |
700 | 1 | a van Swieten, J.4 aut |
700 | 1 | a van Vught, R.4 aut |
700 | 1 | a Verhage, M.4 aut |
700 | 1 | a Verstreken, P.4 aut |
700 | 1 | a Villa, C. E.4 aut |
700 | 1 | a Vogel, J.4 aut |
700 | 1 | a von Kalle, C.4 aut |
700 | 1 | a Walter, J.4 aut |
700 | 1 | a Weckhuysen, S.4 aut |
700 | 1 | a Weichert, W.4 aut |
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700 | 1 | a Community, LifeTime4 aut |
710 | 2 | a Karolinska Institutetb Mikro- och nanosystemteknik4 org |
773 | 0 | t Natured : Springer Natureg 587:7834, s. 377-386q 587:7834<377-386x 0028-0836x 1476-4687 |
856 | 4 | u https://doi.org/10.1038/s41586-020-2715-9y Fulltext |
856 | 4 | u https://www.nature.com/articles/s41586-020-2715-9.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-284813 |
856 | 4 8 | u https://doi.org/10.1038/s41586-020-2715-9 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:145092804 |
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