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Incidence of hypert...
Incidence of hyperthyroidism in Sweden
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- Abraham-Nordling, Mirna (author)
- Karolinska Institutet
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- Byström, Kristina (author)
- Örebro universitet,Hälsoakademin
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- Torring, Ove (author)
- Karolinska Institutet
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- Lantz, Mikael (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
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- Berg, Gertrud, 1944 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology
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- Calissendorff, Jan (author)
- Karolinska Institutet
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- Nyström, Helena Filipsson, 1966 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine
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Jansson, Svante, 1948 (author)
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- Jorneskog, Gun (author)
- Karolinska Institutet
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- Karlsson, F Anders (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Endokrinologi, diabetes och metabolism
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- Nyström, Ernst, 1941 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin,Institute of Medicine, Department of Internal Medicine
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Ohrling, Hans (author)
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Orn, Thomas (author)
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- Hallengren, Bengt (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
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- Wallin, Göran (author)
- Karolinska Institutet
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(creator_code:org_t)
- 2011
- 2011
- English.
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In: European Journal of Endocrinology. - 0804-4643 .- 1479-683X. ; 165:6, s. 899-905
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Abstract
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- Introduction: The incidence of hyperthyroidism has been reported in various countries to be 23-93/100000 inhabitants per year. This extended study has evaluated the incidence for similar to 40% of the Swedish population of 9 million inhabitants. Sweden is considered to be iodine sufficient country. Methods:All patients including children, who were newly diagnosed with overt hyperthyroidism in the years 2003-2005, were prospectively registered in a multicenter study. The inclusion criteria are as follows:clinical symptoms and/or signs of hyperthyroidism with plasma TSH concentration below 0.2 mIE/l and increased plasma levels of free/total triiodothyronine and/or free/total thyroxine. Patients with relapse of hyperthyroidism or thyroiditis were not included. The diagnosis of Graves' disease (GD), toxic multinodular goiter (TMNG) and solitary toxic adenoma (STA), smoking, initial treatment, occurrence of thyroid-associated eye symptoms/signs, and demographic data were registered. Results:A total of 2916 patients were diagnosed with de novo hyperthyroidism showing the total incidence of 27.6/100 000 inhabitants per year. The incidence of GD was 21.0/100 000 and toxic nodular goiter (TNG=STA+TMNG) occurred in 692 patients, corresponding to an annual incidence of 6.5/100 000. The incidence was higher in women compared with men (4.2:1). Seventy-five percent of the patients were diagnosed with GD, in whom thyroid-associated eye symptoms/signs occurred during diagnosis in every fifth patient. Geographical differences were observed. Conclusion:The incidence of hyperthyroidism in Sweden is in a lower range compared with international reports. Seventy-five percent of patients with hyperthyroidism had GD and 20% of them had thyroid-associated eye symptoms/signs during diagnosis. The observed geographical differences require further studies.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Medicin
- Medicine
Publication and Content Type
- ref (subject category)
- art (subject category)
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Abraham-Nordling ...
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Byström, Kristin ...
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Torring, Ove
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Lantz, Mikael
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Berg, Gertrud, 1 ...
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Calissendorff, J ...
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Nyström, Helena ...
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Jansson, Svante, ...
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Jorneskog, Gun
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Karlsson, F Ande ...
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Nyström, Ernst, ...
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Ohrling, Hans
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Orn, Thomas
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Hallengren, Beng ...
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Wallin, Göran
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
- Articles in the publication
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European Journal ...
- By the university
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Örebro University
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Lund University
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Uppsala University
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University of Gothenburg
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Karolinska Institutet