WFRF:(Traherne James A)
Search: WFRF:(Traherne James A) > (2020) > Polymorphism in kil...
- 1 of 1
- Previous record
- Next record
- To hitlist
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04802naa a2200481 4500 | |
| 001 | oai:lup.lub.lu.se:d2246132-7032-4d13-b9c2-945417051ca4 | |
| 003 | SwePub | |
| 008 | 200707s2020 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/d2246132-7032-4d13-b9c2-945417051ca42 URI |
| 024 | 7 | a https://doi.org/10.1016/j.jri.2020.1031692 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Kelemu, Tsehaynehu Addis Ababa University4 aut0 (Swepub:lu)ts0335ke |
| 245 | 1 0 | a Polymorphism in killer cell immunoglobulin-like receptors and human leukocyte antigen-c and predisposition to preeclampsia in Ethiopian pregnant women population |
| 264 | 1 | b Elsevier BV,c 2020 |
| 520 | a Introduction: Preeclampsia (PE) is a human specific pregnancy-related syndrome of unknown etiology that affects 2–8 % of pregnancies. Polymorphism in maternal Killer Cell Immunoglobulin-like Receptors (KIRs) and the ligand fetal Human Leukocyte Antigen-C (HLA-C) may predispose pregnant mothers for PE due to defective trophoblast invasion into the maternal decidua. Our study aimed to investigate the association between maternal KIR and fetal HLA-C polymorphism and PE in Ethiopian pregnant women. Methods: We included a total of 288 (157 controls and 131 PE cases) in a case-controls study at Adama Regional Referral Hospital, Ethiopia. The KIR and HLA-C genotyping was done using traditional polymerase chain reaction on genomic DNA extracted form maternal venous and cord blood followed by 2% agarose gel electrophoresis. Results: The statistical associations between variables were evaluated using Pearson's Chi-square test. P < 0.05, with 95 % confidence interval was considered statistically significant. A significant association was observed between the KIR2DS1 and PE, with a higher frequency (60.5 %) of the gene in the control group. Similarly, a significant association was observed between KIR AA genotype and PE, with a higher frequency (38.2 %) of this genotype in the PE group. Ethiopians share the same risk genotype for PE as seen in previous African and European studies, namely homozygosity of a maternal KIR AA genotype. However, Ethiopians differ from other East African populations by sharing the same protective KIR2DS1 gene as Europeans. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng |
| 653 | a HLA | |
| 653 | a KIR | |
| 653 | a Natural killer cell | |
| 653 | a Preeclampsia | |
| 653 | a Trophoblast cell | |
| 700 | 1 | a Erlandsson, Lenau Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)med-leo |
| 700 | 1 | a Seifu, Danielu University of Global Health Equity (UGHE),Addis Ababa University4 aut |
| 700 | 1 | a Hansson, Evau Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)mphy-eha |
| 700 | 1 | a Abebe, Markosu Armauer Hansen Research Institute4 aut |
| 700 | 1 | a Teklu, Sisayu Addis Ababa University4 aut |
| 700 | 1 | a Girma, Selfuu Armauer Hansen Research Institute4 aut |
| 700 | 1 | a Traherne, James A.u University of Cambridge4 aut |
| 700 | 1 | a Moffett, Ashleyu University of Cambridge4 aut |
| 700 | 1 | a Hansson, Stefan R.u Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)gyn-sha |
| 710 | 2 | a Addis Ababa Universityb Obstetrik och gynekologi, Lund4 org |
| 773 | 0 | t Journal of Reproductive Immunologyd : Elsevier BVg 141q 141x 0165-0378 |
| 856 | 4 | u http://dx.doi.org/10.1016/j.jri.2020.103169x freey FULLTEXT |
| 856 | 4 | u https://doi.org/10.1016/j.jri.2020.103169 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/d2246132-7032-4d13-b9c2-945417051ca4 |
| 856 | 4 8 | u https://doi.org/10.1016/j.jri.2020.103169 |
Find in a library
- Journal of Reproductive Immunology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Kelemu, Tsehayne ...
- Erlandsson, Lena
- Seifu, Daniel
- Hansson, Eva
- Abebe, Markos
- Teklu, Sisay
- show more...
- Girma, Selfu
- Traherne, James ...
- Moffett, Ashley
- Hansson, Stefan ...
- show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Obstetrics Gynae ...
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Basic Medicine
- and Immunology in th ...
- Articles in the publication
- Journal of Repro ...
- By the university
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
