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Mammographic calcif...
Mammographic calcifications undergoing percutaneous biopsy : outcome in women with and without a personal history of breast cancer
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- Bertani, Valeria (author)
- CRO (Centro di Riferimento Oncologico) Aviano National Cancer Institute
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- Berger, Nicole (author)
- University Hospital of Zurich
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- Eberhard, Matthias (author)
- University Hospital of Zurich
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- Lång, Kristina (author)
- Lund University,Lunds universitet,Diagnostisk radiologi, Malmö,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Radiology Diagnostics, Malmö,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
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- Urbani, Martina (author)
- CRO (Centro di Riferimento Oncologico) Aviano National Cancer Institute
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- La Grassa, Manuela (author)
- CRO (Centro di Riferimento Oncologico) Aviano National Cancer Institute
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- Balestreri, Luca (author)
- CRO (Centro di Riferimento Oncologico) Aviano National Cancer Institute
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- Boss, Andreas (author)
- University Hospital of Zurich
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- Frauenfelder, Thomas (author)
- University Hospital of Zurich
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- Marcon, Magda (author)
- University Hospital of Zurich
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(creator_code:org_t)
- 2023-01-04
- 2023
- English 11 s.
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In: Radiologia Medica. - : Springer Science and Business Media LLC. - 0033-8362 .- 1826-6983. ; 128:2, s. 149-159
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Abstract
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- Purpose: To compare the positive predictive values (PPVs) of BI-RADS categories used to assess pure mammographic calcifications in women with and without a previous history of breast cancer (PHBC). Materials and methods: In this retrospective study, all consecutive pure mammographic calcifications (n = 320) undergoing a stereotactic biopsy between 2016 and 2018 were identified. Mammograms were evaluated in consensus by two radiologists according to BI-RADS and blinded to patient history and pathology results. Final pathologic results were used as the standard of reference. PPV of BI-RADS categories were compared between the two groups. Data were evaluated using standard statistics, Mann–Whitney U tests and Chi-square tests. Results: Two hundred sixty-eight patients (274 lesions, median age 54 years, inter-quartile range, 50–65 years) with a PHBC (n = 46) and without a PHBC (n = 222) were included. Overall PPVs were the following: BI-RADS 2, 0% (0 of 56); BI-RADS 3, 9.1% (1 of 11); BI-RADS 4a, 16.2% (6 of 37); BI-RADS 4b, 37.5% (48 of 128); BI-RADS 4c, 47.3% (18 of 38) and BI-RADS 5, 100% (4 of 4). The PPV of BI-RADS categories was similar in patients with and without a PHBC (P =.715). Calcifications were more often malignant in patients with a PHBC older than 10 years (47.3%, 9 of 19) compared to 1–2 years (25%, 1 of 4), 2–5 years (20%, 2 of 10) and 5–10 years (0%, of 13) from the first breast cancer (P =.005). Conclusion: PPV of mammographic calcifications is similar in women with or without PHBC when BI-RADS classification is strictly applied. A higher risk of malignancy was observed in patients with a PHBC longer than 10 years.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- Breast cancer
- Digital mammography
- Microcalcifications
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Bertani, Valeria
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Berger, Nicole
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Eberhard, Matthi ...
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Lång, Kristina
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Urbani, Martina
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La Grassa, Manue ...
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Balestreri, Luca
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Boss, Andreas
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Frauenfelder, Th ...
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Marcon, Magda
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Radiology Nuclea ...
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Radiologia Medic ...
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Lund University