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Sökning: WFRF:(Van Der Steeg Hendrik J.J.) > (2022) > Bowel function and ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005502naa a2200625 4500
001oai:lup.lub.lu.se:4e08332a-ed0d-4671-9b12-139c549b9f65
003SwePub
008220608s2022 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/4e08332a-ed0d-4671-9b12-139c549b9f652 URI
0247 a https://doi.org/10.1016/j.jpedsurg.2022.02.0152 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a van der Steeg, Hendrik J.J.u Radboud University Medical Center4 aut
2451 0a Bowel function and associated risk factors at preschool and early childhood age in children with anorectal malformation type rectovestibular fistula : An ARM-Net consortium study
264 1b Elsevier BV,c 2022
520 a Background: Outcome of patients operated for anorectal malformation (ARM) type rectovestibular fistula (RVF) is generally considered to be good. However, large multi-center studies are scarce, mostly describing pooled outcome of different ARM-types, in adult patients. Therefore, counseling parents concerning the bowel function at early age is challenging. Aim of this study was to evaluate bowel function of RVF-patients at preschool/early childhood age and determine risk factors for poor functional outcome. Methods: A multi-center cohort study was performed. Patient characteristics, associated anomalies, sacral ratio, surgical procedures, post-reconstructive complications, one-year constipation, and Bowel Function Score (BFS) at 4–7 years of follow-up were registered. Groups with below normal (BFS < 17; subgroups ‘poor’ ≤ 11, and ‘fair’ 11 < BFS < 17) and good outcome (BFS ≥ 17) were formed. Univariable analyses were performed to detect risk factors for outcome. Results: The study included 111 RVF-patients. Median BFS was 16 (range 6–20). The ‘below normal’ group consisted of 61 patients (55.0%). Overall, we reported soiling, fecal accidents, and constipation in 64.9%, 35.1% and 70.3%, respectively. Bowel management was performed in 23.4% of patients. Risk factors for poor outcome were tethered cord and low sacral ratio, while sacral anomalies, low sacral ratio, prior enterostomy, post-reconstructive complications, and one-year constipation were for being on bowel management. Conclusions: Although median BFS at 4–7 year follow-up is nearly normal, the majority of patients suffers from some degree of soiling and constipation, and almost 25% needs bowel management. Several factors were associated with poor bowel function outcome and bowel management. Level of Evidence: Level III.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
653 a Anorectal malformation
653 a ARM-Net
653 a Bowel function score
653 a Early childhood
653 a Observational cohort-study
653 a Preschool age
653 a Rectovestibular fistula
653 a Type of study
7001 a van Rooij, Iris A.L.M.u Radboud University Medical Center4 aut
7001 a Iacobelli, Barbara D.u Bambino Gesù Children’s Hospital4 aut
7001 a Sloots, Cornelius E.J.u Sophia Children's Hospital4 aut
7001 a Morandi, Annau Maggiore Hospital Policlinico4 aut
7001 a Broens, Paul M.A.u University Medical Center Groningen4 aut
7001 a Makedonsky, Igoru Children's Hospital Dnepropetrovsk4 aut
7001 a Leon, Francesco Fascettiu University of Padova4 aut
7001 a Schmiedeke, Eberhardu Klinikum Bremen-Mitte4 aut
7001 a Vázquez, Araceli Garcíau 12 de Octubre University Hospital4 aut
7001 a Miserez, Marcu Catholic University of Leuven4 aut
7001 a Lisi, Gabrieleu University G.d'Annunzio of Chieti-Pescara4 aut
7001 a Midrio, Paolau Treviso Hospital4 aut
7001 a Amerstorfer, Eva E.u Medical University of Graz4 aut
7001 a Fanjul, Mariau Hospital Gregorio Maranon4 aut
7001 a Ludwiczek, Johannau Kepler University Hospital Linz4 aut
7001 a Stenström, Pernillau Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Barnkirurgi,Forskargrupper vid Lunds universitet,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Pediatric surgery,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)med-pes
7001 a van der Steeg, Alida F.W.u Princess Maxima Center for Pediatric Oncology/Hematology,Academic Medical Center of University of Amsterdam (AMC)4 aut
7001 a de Blaauw, Ivou Radboud University Medical Center4 aut
7102 a Radboud University Medical Centerb Bambino Gesù Children’s Hospital4 org
7102 a On behalf of the ARM-Net Consortium
7730 t Journal of Pediatric Surgeryd : Elsevier BVg 57:9, s. 89-96q 57:9<89-96x 0022-3468
8564 u http://dx.doi.org/10.1016/j.jpedsurg.2022.02.015x freey FULLTEXT
8564 8u https://lup.lub.lu.se/record/4e08332a-ed0d-4671-9b12-139c549b9f65
8564 8u https://doi.org/10.1016/j.jpedsurg.2022.02.015

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