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FältnamnIndikatorerMetadata
00007225naa a2200577 4500
001oai:DiVA.org:liu-184194
003SwePub
008220406s2022 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:152097791
024a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1841942 URI
024a https://doi.org/10.1016/j.jtcvs.2021.07.0112 DOI
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1520977912 URI
040 a (SwePub)liud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Dagnegård, H.H.u Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark4 aut
2451 0a Survival after aortic root replacement with a stentless xenograft is determined by patient characteristics
264 1b Mosby Inc.; Elsevier Inc.c 2022
338 a electronic2 rdacarrier
520 a Objectives: Our objective was to examine intermediate-term survival and reinterventions in unselected patients, stratified according to indication, who received a Freestyle (Medtronic Inc, Minneapolis, Minn) bioprosthesis as a full aortic root replacement. Methods: Data from medical records were retrospectively collected for patients who had aortic root replacement using Freestyle bioprostheses between 1999 and 2018 at 6 North-Atlantic centers. Survival status was extracted from national registries and results stratified according to indication for surgery. Results: We included 1030 implantations in 1008 patients with elective indications for surgery: aneurysm (39.8%), small root (8.3%), and other (13.8%), and urgent/emergent indications: endocarditis (26.7%) and Stanford type A aortic dissection (11.4%). Across indications, 46.3% were nonelective cases and 34.0% were reoperations. Median age was 66.0 (interquartile range, 58.0-71.8) years and median follow-up was 5.0 (interquartile range, 2.6-7.9) years. Thirty-day mortality varied from 2.9% to 27.4% depending on indication. Intermediate survival for 90-day survivors with elective indications were not different from the general population standardized for age and sex (P = .95, 83, and .16 for aneurysms, small roots, and other, respectively). In contrast, patients with endocarditis and type A dissection had excess mortality (P < .001). Freedom from valve reinterventions was 95.0% and 94.4% at 5 and 8 years, respectively. In all, 52 patients (5.2%) underwent reinterventions, most because of endocarditis. Conclusions: At intermediate term follow-up this retrospective study provides further support for the use of the Freestyle bioprosthesis in the real-world setting of diverse, complex, and often high-risk aortic root replacement and suggests that outcome is determined by patient and disease, rather than by prosthesis, characteristics. © 2021 The Authors
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kirurgi0 (SwePub)302122 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Surgery0 (SwePub)302122 hsv//eng
653 a aortic root replacement; endocarditis; full root bioprosthesis; reinterventions; survival; type A dissections
700a Bekke, K.u Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark4 aut
700a Kolseth, S.M.u Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway4 aut
700a Glaser, N.u Karolinska Institutet4 aut
700a Wallén, C.u Linköpings universitet,Institutionen för hälsa, medicin och vård,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)n/a
700a El-Hamamsy, I.u Montreal Heart Institute, University of Montreal, Montreal, QC, Canada4 aut
700a Vidisson, K.O.u Department of Cardiothoracic Surgery, Landspítali University Hospital, Faculty of Medicine, University of Iceland, Reykjavik, Iceland4 aut
700a Lie, A.S.u Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway4 aut
700a Valentin, J.B.u Danish Center for Clinical Health Services Research (DACS), Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark4 aut
700a Sartipy, U.u Karolinska Institutet4 aut
700a Haaverstad, R.u Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway4 aut
700a Vanky, Farkasu Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Thorax-kärlkliniken i Östergötland4 aut0 (Swepub:liu)farva32
700a Lefebvre, L.u Montreal Heart Institute, University of Montreal, Montreal, QC, Canada4 aut
700a Gudbjartsson, T.u Department of Cardiothoracic Surgery, Landspítali University Hospital, Faculty of Medicine, University of Iceland, Reykjavik, Iceland4 aut
700a Johnsen, S.P.u Danish Center for Clinical Health Services Research (DACS), Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark4 aut
700a Søndergaard, L.u Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark4 aut
700a Thyregod, G.H.u Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark4 aut
700a Lund, J.T.u Cardio Thoracic Surgical Department, Green Lane Division, Auckland City Hospital, Auckland, New Zealand4 aut
700a Ihlemann, N.u Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark4 aut
700a Smerup, M.H.u Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark4 aut
710a Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmarkb Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark4 org
773t Journal of Thoracic and Cardiovascular Surgeryd : Mosby Inc.; Elsevier Inc.g 164:6, s. 1712-1724q 164:6<1712-1724x 0022-5223x 1097-685X
856u https://liu.diva-portal.org/smash/get/diva2:1650274/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856u http://www.jtcvs.org/article/S0022522321010424/pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-184194
8564 8u https://doi.org/10.1016/j.jtcvs.2021.07.011
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:152097791

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