SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Yadegarfar Mohammad E.)
 

Sökning: WFRF:(Yadegarfar Mohammad E.) > (2014) > Gender and telomere...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005750naa a2201045 4500
001oai:DiVA.org:umu-87398
003SwePub
008140331s2014 | |||||||||||000 ||eng|
009oai:lup.lub.lu.se:ca7f11a7-3f72-413a-8a55-2a5f13d87137
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-873982 URI
0247 a https://doi.org/10.1016/j.exger.2013.12.0042 DOI
0247 a https://lup.lub.lu.se/record/42230412 URI
040 a (SwePub)umud (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a for2 swepub-publicationtype
1001 a Gardner, Michael4 aut
2451 0a Gender and telomere length :b Systematic review and meta-analysis
264 1b Elsevier,c 2014
338 a print2 rdacarrier
520 a Background: It is widely believed that females have longer telomeres than males, although results from studies have been contradictory. Methods: We carried out a systematic review and meta-analyses to test the hypothesis that in humans, females have longer telomeres than males and that this association becomes stronger with increasing age. Searches were conducted in EMBASE and MEDLINE (by November 2009) and additional datasets were obtained from study investigators. Eligible observational studies measured telomeres for both females and males of any age, had a minimum sample size of 100 and included participants not part of a diseased group. We calculated summary estimates using random-effects meta-analyses. Heterogeneity between studies was investigated using sub-group analysis and meta-regression. Results: Meta-analyses from 36 cohorts (36,230 participants) showed that on average females had longer telomeres than males (standardised difference in telomere length between females and males 0.090, 95% CI 0.015, 0.166; age-adjusted). There was little evidence that these associations varied by age group (p = 1.00) or cell type (p = 0.29). However, the size of this difference did vary by measurement methods, with only Southern blot but neither real-time PCR nor Flow-FISH showing a significant difference. This difference was not associated with random measurement error. Conclusions: Telomere length is longer in females thanmales, although this difference was not universally found in studies that did not use Southern blot methods. Further research on explanations for the methodological differences is required. (C) 2013 Published by Elsevier Inc.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Annan medicin och hälsovetenskapx Gerontologi, medicinsk/hälsovetenskaplig inriktning0 (SwePub)305022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Other Medical and Health Sciencesx Gerontology, specialising in Medical and Health Sciences0 (SwePub)305022 hsv//eng
653 a Gender
653 a Telomere length
653 a Systematic review and meta-analysis
653 a Measurement methods
653 a Epidemiology
7001 a Bann, David4 aut
7001 a Wiley, Laura4 aut
7001 a Cooper, Rachel4 aut
7001 a Hardy, Rebecca4 aut
7001 a Nitsch, Dorothea4 aut
7001 a Martin-Ruiz, Carmen4 aut
7001 a Shiels, Paul4 aut
7001 a Sayer, Avan Aihie4 aut
7001 a Barbieri, Michelangela4 aut
7001 a Bekaert, Sofie4 aut
7001 a Bischoff, Claus4 aut
7001 a Brooks-Wilson, Angela4 aut
7001 a Chen, Wei4 aut
7001 a Cooper, Cyrus4 aut
7001 a Christensen, Kaare4 aut
7001 a De Meyer, Tim4 aut
7001 a Deary, Ian4 aut
7001 a Der, Geoff4 aut
7001 a Roux, Ana Diez4 aut
7001 a Fitzpatrick, Annette4 aut
7001 a Hajat, Anjum4 aut
7001 a Halaschek-Wiener, Julius4 aut
7001 a Harris, Sarah4 aut
7001 a Hunt, Steven C.4 aut
7001 a Jagger, Carol4 aut
7001 a Jeon, Hyo-Sung4 aut
7001 a Kaplan, Robert4 aut
7001 a Kimura, Masayuki4 aut
7001 a Lansdorp, Peter4 aut
7001 a Li, Changyong4 aut
7001 a Maeda, Toyoki4 aut
7001 a Mangino, Massimo4 aut
7001 a Nawrot, Tim S.4 aut
7001 a Nilsson, Peteru Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)medf-pni
7001 a Nordfjäll, Katarinau Umeå universitet,Institutionen för medicinsk biovetenskap4 aut0 (Swepub:umu)kaanll02
7001 a Paolisso, Giuseppe4 aut
7001 a Ren, Fu4 aut
7001 a Riabowol, Karl4 aut
7001 a Robertson, Tony4 aut
7001 a Roos, Goran4 aut
7001 a Staessen, Jan A.4 aut
7001 a Spector, Tim4 aut
7001 a Tang, Nelson4 aut
7001 a Unryn, Brad4 aut
7001 a van der Harst, Pim4 aut
7001 a Woo, Jean4 aut
7001 a Xing, Chao4 aut
7001 a Yadegarfar, Mohammad E.4 aut
7001 a Park, Jae Yong4 aut
7001 a Young, Neal4 aut
7001 a Kuh, Diana4 aut
7001 a von Zglinicki, Thomas4 aut
7001 a Ben-Shlomo, Yoav4 aut
7102 a Internmedicin - epidemiologib Forskargrupper vid Lunds universitet4 org
7730 t Experimental Gerontologyd : Elsevierg 51, s. 15-27q 51<15-27x 0531-5565x 1873-6815
8564 u https://lirias.kuleuven.be/bitstream/123456789/449926/1/14-08-P.pdf
8564 u http://www.ncbi.nlm.nih.gov/pubmed/24365661?dopt=Abstracty FULLTEXT
8564 u http://dx.doi.org/10.1016/j.exger.2013.12.004y FULLTEXT
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-87398
8564 8u https://doi.org/10.1016/j.exger.2013.12.004
8564 8u https://lup.lub.lu.se/record/4223041

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy