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Optimised synthetic...
Optimised synthetic route for tuneable shell Si02@Fe304 core-shell nanoparticles
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- Vogt, Carmen M. (author)
- KTH,Funktionella material, FNM
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- Toprak, Muhammet (author)
- KTH,Funktionella material, FNM
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Shi, J. (author)
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Torres, N. F. (author)
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Fadeel, B. (author)
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Laurent, S. (author)
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Bridot, J. -L (author)
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Müller, R. N. (author)
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- Muhammed, Mamoun (author)
- KTH,Funktionella material, FNM
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show less...
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(creator_code:org_t)
- Materials Research Society, 2009
- 2009
- English.
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In: Advances in material design for regenerative medicine, drug delivery, and targeting/imaging. - : Materials Research Society. - 9781605111124 ; , s. 209-214
- Related links:
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https://urn.kb.se/re...
Abstract
Subject headings
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- Multifunctional nanoparticles (that have in their structure different components that can perform various functions) are subject of intensive research activities as they find a large variety of applications in numerous biomedical fields from enhancement of image contrast in MRI to different magnetically controllable drug delivery systems. In this study we report on the synthesis of well-separated, monodisperse single core-shell Si02@Fe304 nanoparticles with an overall diameter of ̃30 nm. The influence of stirring rate and reaction time on synthesis of tuneable shell thickness core-shell nanoparticles is reported. Particles' cell toxicity and performance as MRI contrast agents were also studied due to their promising biological applications (as contrast agents, cell labelling and separation, drug delivery systems, etc.) and results are promising in terms of MRI performance as well as having no significant cytotoxicity.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Kemiteknik -- Polymerteknologi (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Chemical Engineering -- Polymer Technologies (hsv//eng)
Keyword
- Biological applications
- Biomedical fields
- Cell labelling
- Cell toxicity
- Contrast agent
- Core-shell
- Core-shell nanoparticles
- Drug delivery system
- Image contrasts
- Intensive research
- Monodisperse
- MRI contrast agents
- Multi-functional nanoparticles
- Reaction time
- Shell thickness
- Stirring rates
- Synthetic routes
- Cytotoxicity
- Drug delivery
- Nanoparticles
- Synthesis (chemical)
- Shells (structures)
Publication and Content Type
- ref (subject category)
- kon (subject category)
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