Multi-scale mechanics of traumatic brain injury: predicting axonal strains from head loads

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: id:"swepub:oai:DiVA.org:kth-91175" > Multi-scale mechani...

1 av 1
Föregående post
Nästa post
Till träfflistan

LIBRIS Formathandbok (Information om MARC21)

Fältnamn	Indikatorer	Metadata
000		03485naa a2200469 4500
001		oai:DiVA.org:kth-91175
003		SwePub
008		120308s2013 \| \|\|\|\|\|\|\|\|\|\|\|000 \|\|eng\|
024	7	a https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-911752 URI
024	7	a https://doi.org/10.1007/s10237-012-0387-62 DOI
040		a (SwePub)kth
041		a engb eng
042		9 SwePub
072	7	a ref2 swepub-contenttype
072	7	a art2 swepub-publicationtype
100	1	a Cloots, Rudy J.H.u Eindhoven University of Technology, Department of Mechanical Engineering4 aut
245	1 0	a Multi-scale mechanics of traumatic brain injury :b predicting axonal strains from head loads
264		c 2012-03-21
264	1	b Springer Science and Business Media LLC,c 2013
338		a print2 rdacarrier
500		a QC 20130207
520		a The length scales involved in the development of diffuse axonal injury typically range from the head level (i.e., mechanical loading) to the cellular level. The parts of the brain that are vulnerable to this type of injury are mainly the brainstem and the corpus callosum, which are regions with highly anisotropically oriented axons. Within these parts, discrete axonal injuries occur mainly where the axons have to deviate from their main course due to the presence of an inclusion. The aim of this study is to predict axonal strains as a result of a mechanical load at the macroscopic head level. For this, a multi-scale finite element approach is adopted, in which a macro-level head model and a micro-level critical volume element are coupled. The results show that the axonal strains cannot be trivially correlated to the tissue strain without taking into account the axonal orientations, which indicates that the heterogeneities at the cellular level play an important role in brain injury and reliable predictions thereof. In addition to the multi-scale approach, it is shown that a novel anisotropic equivalent strain measure can be used to assess these micro-scale effects from head-level simulations only.
650	7	a TEKNIK OCH TEKNOLOGIERx Medicinteknikx Annan medicinteknik0 (SwePub)206992 hsv//swe
650	7	a ENGINEERING AND TECHNOLOGYx Medical Engineeringx Other Medical Engineering0 (SwePub)206992 hsv//eng
650	7	a TEKNIK OCH TEKNOLOGIERx Maskinteknikx Teknisk mekanik0 (SwePub)203012 hsv//swe
650	7	a ENGINEERING AND TECHNOLOGYx Mechanical Engineeringx Applied Mechanics0 (SwePub)203012 hsv//eng
653		a Traumatic brain injury
653		a TBI
653		a Diffuse axonal injury
653		a DAI
653		a Injury criteria
653		a Head model
653		a Finite element method
653		a Multi-scale
700	1	a van Dommelen, J.A.W.u Eindhoven University of Technology, Department of Mechanical Engineering4 aut
700	1	a Kleiven, Svein,d 1966-u KTH,Neuronik4 aut0 (Swepub:kth)u1aqbjml
700	1	a Geers, Marcu Eindhoven University of Technology, Department of Mechanical Engineering4 aut
710	2	a Eindhoven University of Technology, Department of Mechanical Engineeringb Neuronik4 org
773	0	t Biomechanics and Modeling in Mechanobiologyd : Springer Science and Business Media LLCg 12:1, s. 137-150q 12:1<137-150x 1617-7959x 1617-7940
856	4	u https://link.springer.com/content/pdf/10.1007%2Fs10237-012-0387-6.pdf
856	4 8	u https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-91175
856	4 8	u https://doi.org/10.1007/s10237-012-0387-6

Hitta via bibliotek

Biomechanics and Modeling in Mechanobiology (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

1 av 1
Föregående post
Nästa post
Till träfflistan

Hitta mer i SwePub

Av författaren/redakt...: Cloots, Rudy J.H ...; van Dommelen, J. ...; Kleiven, Svein, ...; Geers, Marc

Om ämnet

TEKNIK OCH TEKNOLOGIER: TEKNIK OCH TEKNO ...; och Medicinteknik; och Annan medicintek ...

TEKNIK OCH TEKNOLOGIER: TEKNIK OCH TEKNO ...; och Maskinteknik; och Teknisk mekanik

Artiklar i publikationen: Biomechanics and ...

Av lärosätet: Kungliga Tekniska Högskolan

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se