id:"swepub:oai:DiVA.org:liu-110998"
Search: id:"swepub:oai:DiVA.org:liu-110998" > Hepatocyte growth f...
- 1 of 1
- Previous record
- Next record
- To hitlist
Hepatocyte growth factor is a reliable marker for efficient anti-bacterial therapy within the first day of treatment
-
- Abednazari, Hossin (author)
- Linköpings universitet,Avdelningen för mikrobiologi och molekylär medicin,Hälsouniversitetet,PEAS Institute, Linköping
-
- Brudin, Lars (author)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet,Fysiologiska kliniken US
-
- Almroth, Gabriel (author)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för läkemedelsforskning,Hälsouniversitetet,Njurmedicinska kliniken US
- show more...
- show less...
- (creator_code:org_t)
- Scientific Research Publishing, 2014
- 2014
- English.
- In: Advances in Bioscience and Biotechnology. - : Scientific Research Publishing. - 2156-8456 .- 2156-8502. ; 5:10, s. 823-830
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Rapid diagnosis and choice of appropriate antibiotic treatment might be life-saving in serious infectious diseases. Still the available markers that can evaluate and monitor the diagnosis and treatment are few. Hepatocyte growth factor (HGF) has been studied as a potent regenerative factor produced and released during injuries such as infectious diseases. Monitoring of HGF levels might predict therapy results better than C-reactive protein (CRP) within the first day of treatment in pneumonia. For further investigation of previous observations we aimed to study HGF as a first-day marker in over-representing infectious diseases in comparison to procalcitonin (PCT), CRP and body temperature. Fifty-one patients with community acquired infectious diseases were included consequently at admittance and the serum samples were collected before and within 18 - 24 hours of treatment. HGF levels decreased significantly in case of efficient antibiotic therapy and HGF was shown to be better than PCT, CRP and body temperature to evaluate treatment. In patients with pneumonia, monitoring of HGF was most reasonable. HGF might be used as a therapeutic marker within the first day of empiric antibiotic treatment during infection.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Hepatocyte Growth Factor
- C-Reactive Protein
- Procalcitonin
- Temperature
- Antibacterial Therapy
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Advances in Bioscience and Biotechnology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Abednazari, Hoss ...
- Brudin, Lars
- Almroth, Gabriel
- Nilsson, Ingela
- Nayeri, Fariba
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- Articles in the publication
- Advances in Bios ...
- By the university
- Linköping University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
