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Structural advances...
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Zacharchenko, ThomasInstitute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom
(författare)
Structural advances on titin : towards an atomic understanding of multi-domain functions in myofilament mechanics and scaffolding.
- Artikel/kapitelEngelska2015
Förlag, utgivningsår, omfång ...
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Portland Press Ltd,2015
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Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-143659
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-143659URI
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https://doi.org/10.1042/BST20150084DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Titin is a gigantic filamentous protein of the muscle sarcomere that plays roles in myofibril mechanics and homoeostasis. 3D-structures of multi-domain fragments of titin are now available that start revealing the molecular mechanisms governing its mechanical and scaffolding functions. This knowledge is now being translated into the fabrication of self-assembling biopolymers. Here we review the structural advances on titin, the novel concepts derived from these and the emerging translational avenues.
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von Castelmur, EleonoreInstitute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom, Netherlands Cancer Institute, Amsterdam, Netherlands(Swepub:liu)elevo74
(författare)
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Rigden, Daniel JInstitute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom
(författare)
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Mayans, OlgaInstitute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom
(författare)
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Institute of Integrative Biology, University of Liverpool, Liverpool, United KingdomInstitute of Integrative Biology, University of Liverpool, Liverpool, United Kingdom, Netherlands Cancer Institute, Amsterdam, Netherlands
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Biochemical Society Transactions: Portland Press Ltd43:5, s. 850-50300-51271470-8752
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