Prospective study of symptoms and gastro-oesophageal reflux 10 years after posterior partial fundoplication

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Background:This was a prospective study of symptoms, and short-term and long-term reflux competence after partial fundoplication.Methods:Some 101 patients were operated consecutively with posterior partial (270°) fundoplication. Indications for surgery were reflux disease without erosive oesophagitis in 25 patients, moderate oesophagitis in 43, severe oesophagitis in 25 and paraoesophageal hernia in eight. Symptom score, manometry and pH tests were performed before operation, 6 months after operation and after 6–14 years.Results:All patients (n = 101) were free from heartburn and regurgitation at early follow-up. There was evidence of clinical recurrence at late follow-up (n = 87) in two of 22 patients without oesophagitis before operation, two of 39 with moderate oesophagitis before operation and three of 19 patients with severe oesophagitis before operation; 92 per cent had good reflux control at late follow-up.ConclusionPosterior partial fundoplication shows excellent reflux control at early follow-up. Ten years later fewer than 10 per cent of patients have recurrence, which is more common in patients who had severe oesophagitis before operation.

Av författaren/redakt...: Franzén, Thomas, ...; Boström, J.; Tibbling Grahn, ...; Johansson, Karl- ...

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