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Sökning: id:"swepub:oai:DiVA.org:liu-67638" > Frailty as a Predic...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003598nam a2200361 4500
001oai:DiVA.org:liu-67638
003SwePub
008110420| | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-676382 URI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a vet2 swepub-contenttype
072 7a ovr2 swepub-publicationtype
1001 a Ekerstad, Niklas,d 1969-u Linköpings universitet,Utvärdering och hälsoekonomi,Hälsouniversitetet4 aut0 (Swepub:liu)nikek11
2451 0a Frailty as a Predictor of Short-Term Outcomes for Elderly Patients with non-ST-Elevation Myocardial Infarction (NSTEMI)
338 a print2 rdacarrier
520 a Background – For the large and growing population of elderly patients with cardiovascular disease it is important to identify clinically relevant measures of biological age and their contribution to risk. Frailty is an emerging concept in medicine denoting increased vulnerability and decreased physiologic reserves. We analyzed how the variable frailty predicts short-term outcomes for elderly NSTEMI patients. Methods and Results – Patients, aged 75 years or older, with diagnosed NSTEMI were included at three centers, and clinical data including judgement of frailty were collected prospectively. Frailty was defined according to the Canadian Study of Health and Aging (CSHA) Clinical Frailty Scale (CFS). Of 307 patients, 150 (48.5%) were considered frail. Frail patients were slightly older and presented with a greater burden of comorbidity. By multiple logistic regression, frailty was found to be a strong independent risk factor for inhospital mortality, one-month mortality (OR 3.8, 95% CI 1.3 to 10.8) and the primary composite outcome (OR 2.2, 95% CI 1.3 to 3.7). Particularly frail patients with a high comorbidity burden manifested a markedly increased risk for the primary composite outcome. By multiple linear regression, frailty was identified as a strong independent predictor for prolonged hospital care (frail 13.4 bed days, non-frail 7.5 bed days; P<0.0001). Conclusions - Frailty is a strong independent predictor of in-hospital mortality, one-month mortality, prolonged hospital care and the primary composite outcome. The combined use of frailty and comorbidity may constitute an ultimate risk prediction concept regarding cardiovascular patients with complex needs.
653 a Elderly
653 a frailty
653 a NSTEMI
653 a co-morbidity
653 a outcomes
653 a MEDICINE
653 a MEDICIN
7001 a Swahn, Evau Östergötlands Läns Landsting,Linköpings universitet,Kardiologi,Hälsouniversitetet,Kardiologiska kliniken US4 aut0 (Swepub:liu)evasw45
7001 a Janzon, Magnusu Östergötlands Läns Landsting,Linköpings universitet,Kardiologi,Hälsouniversitetet,Kardiologiska kliniken US4 aut0 (Swepub:liu)magja75
7001 a Alfredsson, Joakimu Östergötlands Läns Landsting,Linköpings universitet,Kardiologi,Hälsouniversitetet,Kardiologiska kliniken US4 aut0 (Swepub:liu)joaal38
7001 a Löfmark, Ruriku Stockholm Centre for Healthcare Ethics, LIME, Karolinska Institutet, Stockholm4 aut
7001 a Lindenberger, Marcusu Linköpings universitet,Fysiologi,Hälsouniversitetet4 aut0 (Swepub:liu)marli51
7001 a Carlsson, Peru Linköpings universitet,Utvärdering och hälsoekonomi,Hälsouniversitetet4 aut0 (Swepub:liu)perca23
7102 a Linköpings universitetb Utvärdering och hälsoekonomi4 org
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-67638

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