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Preparation and Cha...
Preparation and Characterization of Softwood and Hardwood Nanofibril Hydrogels: Toward Wound Dressing Applications
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- Baş, Yağmur (author)
- Luleå tekniska universitet,Materialvetenskap,Division of Materials Science, Luleå University of Technology, Sweden
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- Berglund, Linn (author)
- Luleå tekniska universitet,Materialvetenskap,Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.
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- Niittylä, Totte (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för skoglig genetik och växtfysiologi,Department of Forest Genetics and Plant Physiology
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- Zattarin, Elisa, Doktorand, 1992- (author)
- Linköpings universitet,Tekniska fakulteten,Biofysik och bioteknik
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- Aili, Daniel (author)
- Linköpings universitet,Tekniska fakulteten,Biofysik och bioteknik
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- Sotra, Zeljana (author)
- Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Katastrofmedicinskt centrum
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- Rinklake, Ivana (author)
- Linköpings universitet,Medicinska fakulteten,Institutionen för biomedicinska och kliniska vetenskaper,Region Östergötland, Katastrofmedicinskt centrum
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- Junker, Johan, 1980- (author)
- Linköpings universitet,Medicinska fakulteten,Avdelningen för kirurgi, ortopedi och onkologi,Region Östergötland, Katastrofmedicinskt centrum
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- Rakar, Jonathan, 1983- (author)
- Linköpings universitet,Medicinska fakulteten,Avdelningen för kirurgi, ortopedi och onkologi,Region Östergötland, Katastrofmedicinskt centrum
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- Oksman, Kristiina, 1959- (author)
- Luleå tekniska universitet,Materialvetenskap,Department of Mechanical & Industrial Engineering (MIE), University of Toronto, Toronto, Ontario M5S 3G8, Canada,Division of Materials Science, Luleå University of Technology, Sweden ; Department of Mechanical & Industrial Engineering (MIE), University of Toronto, Ontario, Canada
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(creator_code:org_t)
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- American Chemical Society (ACS), 2023
- 2023
- English.
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In: Biomacromolecules. - : American Chemical Society (ACS). - 1525-7797 .- 1526-4602. ; 24:12, s. 5605-5619
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https://ltu.diva-por... (primary) (Raw object)
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https://doi.org/10.1...
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Abstract
Subject headings
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- Hydrogels of cellulose nanofibrils (CNFs) are promising wound dressing candidates due to their biocompatibility, high water absorption, and transparency. Herein, two different commercially available wood species, softwood and hardwood, were subjected to TEMPO-mediated oxidation to proceed with delignification and oxidation in a one-pot process, and thereafter, nanofibrils were isolated using a high-pressure microfluidizer. Furthermore, transparent nanofibril hydrogel networks were prepared by vacuum filtration. Nanofibril properties and network performance correlated with oxidation were investigated and compared with commercially available TEMPO-oxidized pulp nanofibrils and their networks. Softwood nanofibril hydrogel networks exhibited the best mechanical properties, and in vitro toxicological risk assessment showed no detrimental effect for any of the studied hydrogels on human fibroblast or keratinocyte cells. This study demonstrates a straightforward processing route for direct oxidation of different wood species to obtain nanofibril hydrogels for potential use as wound dressings, with softwood having the most potential.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Materialteknik -- Pappers-, massa- och fiberteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Materials Engineering -- Paper, Pulp and Fiber Technology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomaterialvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomaterials Science (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Materialteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Materials Engineering (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Kemiteknik -- Polymerteknologi (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Chemical Engineering -- Polymer Technologies (hsv//eng)
Keyword
- Trä och bionanokompositer
- Wood and Bionanocomposites
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Baş, Yağmur
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Berglund, Linn
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Niittylä, Totte
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Zattarin, Elisa, ...
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Aili, Daniel
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Sotra, Zeljana
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Rinklake, Ivana
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Junker, Johan, 1 ...
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Rakar, Jonathan, ...
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Oksman, Kristiin ...
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- About the subject
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Materials Engine ...
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and Paper Pulp and F ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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and Biomaterials Sci ...
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Materials Engine ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Chemical Enginee ...
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and Polymer Technolo ...
- Articles in the publication
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Biomacromolecule ...
- By the university
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Luleå University of Technology
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Linköping University
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Swedish University of Agricultural Sciences