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Self-management and...
Self-management and hospitalization in 615 Swedish patients with Addison's disease during the COVID-19 pandemic : a retrospective study
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- Öster, Sara (författare)
- Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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- Esposito, Daniela (författare)
- Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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- Aranda-Guillén, Maribel (författare)
- Center for Molecular Medicine, Department of Medicine (Solna), Karolinska Institutet, Stockholm, Sweden
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- Åkerman, Anna-Karin (författare)
- Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; Department of Internal Medicine, School of Health and Medical Sciences, Örebro University, Örebro, Sweden
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- Wahlberg, Jeanette, 1969- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper
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- Husebye, Eystein Sverre (författare)
- Department of Clinical Science, University of Bergen, N-5021 BergenNorway; Department of Medicine, Haukeland University Hospital, N-5021 Bergen, Norway
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- Kämpe, Olle (författare)
- Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden; Center for Molecular Medicine, Department of Medicine (Solna), Karolinska Institutet, Stockholm, Sweden
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- Botusan, Ileana Ruxandra (författare)
- Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden; Center for Molecular Medicine, Department of Medicine (Solna), Karolinska Institutet, Stockholm, Sweden; Center for Diabetes, Academic Specialist Centrum, Stockholm, Sweden
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- Dahlqvist, Per (författare)
- Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
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- Bergthorsdottir, Ragnhildur (författare)
- Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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- Bensing, Sophie (författare)
- Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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(creator_code:org_t)
- 2023-01-31
- 2023
- Engelska.
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Ingår i: European Journal of Endocrinology. - : Bioscientifica. - 0804-4643 .- 1479-683X. ; 188:2
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- OBJECTIVE: Autoimmune Addison's disease (AAD) entails a chronic adrenal insufficiency and is associated with an increased risk of severe infections. It is, however, unknown how patients with AAD were affected by the coronavirus disease 2019 (COVID-19) pandemic of 2020-2021. The aim of this study was to investigate the incidence of COVID-19 in patients with AAD in Sweden, the self-adjustment of medications during the disease, impact on social aspects and treatment during hospitalization. Additionally, we investigated if there were any possible risk factors for infection and hospitalization.DESIGN AND METHODS: Questionnaires were sent out from April to October 2021 to 813 adult patients with AAD in the Swedish Addison registry. The questionnaires included 55 questions inquiring about COVID-19 sickness, hospital care, medications, and co-morbidities, focusing on the pre-vaccine phase.RESULTS: Among the 615 included patients with AAD, COVID-19 was reported by 17% of which 8.5% required hospital care. Glucocorticoid treatment in hospitalized patients varied. For outpatients 85% increased their glucocorticoid dosage during sickness. Older age (p=0.002) and hypertension (p=0.014) were associated with an increased risk of hospital care while younger age (p<0.001) and less worry about infection (p=0.030) correlated with a higher risk of COVID-19.CONCLUSIONS: In the largest study to date examining AAD during the COVID-19 pandemic, we observed that although one fifth of the cohort contracted COVID-19 few patients required hospital care. A majority of the patients applied general recommended sick-rules despite reporting limited communication with healthcare during the pandemic.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- COVID-19
- adrenal insufficiency
- autoimmune Addison’s disease
- self-management
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- ref (ämneskategori)
- art (ämneskategori)
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Öster, Sara
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Esposito, Daniel ...
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Aranda-Guillén, ...
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Åkerman, Anna-Ka ...
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Wahlberg, Jeanet ...
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Husebye, Eystein ...
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Kämpe, Olle
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Botusan, Ileana ...
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Dahlqvist, Per
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Bergthorsdottir, ...
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Bensing, Sophie
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