id:"swepub:oai:DiVA.org:oru-11117"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02749naa a2200361 4500 | |
| 001 | oai:DiVA.org:oru-11117 | |
| 003 | SwePub | |
| 008 | 100616s2006 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-111172 URI |
| 040 | a (SwePub)oru | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Danielsson, P.4 aut |
| 245 | 1 0 | a Systemic white blood and endothelial cell response after revascularization of critical limb ischemia is only influenced in case of ischemic ulcers |
| 264 | 1 | c 2006 |
| 338 | a print2 rdacarrier | |
| 520 | a AIM: The aim of this study was to study the inflammatory response to open revascularization of an ischemic leg in terms of activation of white blood cells (WBC), platelets and endothelial cells. DESIGN: prospective study. METHODS: Venous samples from 21 patients suffering critical limb ischemia (CLI) were drawn before, and 4 weeks after (20 patients) revascularization. Total WBC, differentiated WBC, and platelets were counted. Expression of CD11b/CD18 on granulocytes and monocytes and CD41 on platelets was measured by flow cytometry. Soluble endothelial markers (sICAM-1, sVCAM-1, sE-selectin and sP-selectin) were analysed with ELISA. RESULTS: WBC and granulocyte count decreased in the subgroup of patients with ulcer and gangrene but no change in activation of WBC was recorded. The endothelial marker sICAM-1 decreased while VCAM-1 increased following surgery, most evident in the subgroup with ulcers and gangrene. CONCLUSIONS: This study shows that revascularization of CLI does not significantly influence the inflammatory response in patients with rest pain only, but a limited response of down regulation was found in the ulcer/gangrene patients probably as an effect of healing ulcers. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 653 | a MEDICINE | |
| 653 | a MEDICIN | |
| 653 | a Cardiology | |
| 653 | a Kardiologi | |
| 653 | a Cardiology | |
| 653 | a Kardiologi | |
| 700 | 1 | a Truedsson, L.4 aut |
| 700 | 1 | a Norgren, Larsu Örebro universitet,Institutionen för klinisk medicin4 aut0 (Swepub:oru)lsnn |
| 710 | 2 | a Örebro universitetb Institutionen för klinisk medicin4 org |
| 773 | 0 | t International Journal of Angiologyg 25:3, s. 310-315q 25:3<310-315x 0392-9590x 1827-1839 |
| 856 | 4 | u https://www.minervamedica.it/en/journals/international-angiology/article.php?cod=R34Y2006N03A0310y Free full text |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-11117 |
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