Gas chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry methods for the determination of environmental contaminants

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: id:"swepub:oai:DiVA.org:oru-51727" > Gas chromatography-...

1 of 1
Previous record
Next record
To hitlist

Gas chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry methods for the determination of environmental contaminants

Geng, Dawei, 1986- (author): Örebro universitet,Institutionen för naturvetenskap och teknik

van Bavel, Bert, Professor (thesis advisor): Örebro universitet,Institutionen för naturvetenskap och teknik

Ericson Jogsten, Ingrid, PhD (thesis advisor): Örebro universitet,Institutionen för naturvetenskap och teknik

Hagberg, Jessika, Docent (thesis advisor): Örebro universitet,Institutionen för naturvetenskap och teknik

Wang, Thanh, PhD (thesis advisor): Örebro universitet,Institutionen för naturvetenskap och teknik

Fiedler, Heidi, PhD (thesis advisor): Örebro universitet,Institutionen för naturvetenskap och teknik

Olie, Kees, Docent (opponent): University of Amsterdam

show less...

(creator_code:org_t)

Örebro : Örebro university, 2016
English 83 s.
Series: Örebro Studies in Chemistry, 1651-4270 ; 17

Related links:: https://oru.diva-por... (Preview); show more...; https://oru.diva-por...; https://oru.diva-por... (primary) (Raw object); https://oru.diva-por...; https://urn.kb.se/re...; show less...

Doctoral thesis (other academic/artistic)

Abstract Subject headings

The recent developments and improvements of instrumental methods for the analyses of the environmental contaminants, especially the persistent organic pollutants (POPs), have made it possible to detect and quantify these at very low concentrations in environmental and biotic matrices.The main objective of this thesis is to demonstrate the capability of the atmospheric pressure chemical ionization technique (APCI), using gas chromatography coupled to tandem mass spectrometry for the determination of a wide range of environmental contaminants, including the POPs regulated by Stockholm Convention, such as polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), but also the derivates of PBDEs and novel brominated flame retardants (NBFRs).The APCI was operated in charge transfer condition, preferably producing molecular ions. Multiple reaction monitoring (MRM) experiments were optimized by adjusting cone voltage, collision energy and dwell time. Optimization of source parameters, such as gas flows and temperatures was also performed. Low concentration standards were analyzed, achieving a visible chromatographic peak for 2 fg 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) demonstrating the excellent sensitivity of the system. Adequate linearity and repeatability were observed for all the studied compounds. The performance of APCI methods was validated against the conventional methods using gas chromatography coupled to high resolution mass spectrometry for chlorinated compounds in a wide range of matrices including environmental, air, human and food matrices.The GC-APCI-MS/MS method was successfully applied to a set of 75 human serum samples to study the circulating levels of POPs in epidemiologic studies. Moreover the method was utilized to establish temporal trends of POPs in osprey eggs samples collected during the past five decades.

Subject headings

NATURVETENSKAP -- Kemi (hsv//swe)
NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
NATURVETENSKAP -- Kemi -- Annan kemi (hsv//swe)
NATURAL SCIENCES -- Chemical Sciences -- Other Chemistry Topics (hsv//eng)

Keyword

PCDD/Fs
PCBs
OCPs
PBDEs
NBFRs
APCI
MS/MS
HRMS
human serum
osprey egg
Chemistry
Kemi

Publication and Content Type

vet (subject category)
dok (subject category)

Find in a library

Gas chromatography-atmospheric pressure chemical ionization-tandem mass spectrom... (Search the publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Geng, Dawei, 198 ...; van Bavel, Bert, ...; Ericson Jogsten, ...; Hagberg, Jessika ...; Wang, Thanh, PhD; Fiedler, Heidi, ...; show more...; Olie, Kees, Doce ...; show less...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Chemical Science ...

NATURAL SCIENCES: NATURAL SCIENCES; and Chemical Science ...; and Other Chemistry ...

Parts in the series: Örebro Studies i ...

By the university: Örebro University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se