Sökning: id:"swepub:oai:DiVA.org:oru-59088" > Severe infections a...
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001 | oai:DiVA.org:oru-59088 | |
003 | SwePub | |
008 | 170814s2017 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:137106789 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-590882 URI |
024 | 7 | a https://doi.org/10.1177/20474873177240092 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1371067892 URI |
040 | a (SwePub)orud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Bergh, Cecilia,d 1972-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)cbh |
245 | 1 0 | a Severe infections and subsequent delayed cardiovascular disease |
264 | c 2017-08 | |
264 | 1 | b Sage Publications,c 2017 |
338 | a print2 rdacarrier | |
500 | a Funding Agency:UK Economic and Social Research Council (ESRC) RES-596-28-0001 ES/JO19119/1 | |
520 | a Background: Severe infections in adulthood are associated with subsequent short-term cardiovascular disease. Whether hospital admission for sepsis or pneumonia is associated with persistent increased risk (over a year after infection) is less well established.Design: The design of this study was as a register-based cohort study.Methods: Some 236,739 men born between 1952-1956 were followed from conscription assessments in adolescence to 2010. All-cause cardiovascular disease ( n = 46,754), including coronary heart disease ( n = 10,279) and stroke ( n = 3438), was identified through national registers 1970-2010 (at ages 18-58 years).Results: Sepsis or pneumonia in adulthood (resulting in hospital admission) are associated with increased risk of cardiovascular disease in the years following infection. The risk is highest during the first year after the infection, with an adjusted hazard ratio (and 95% confidence intervals) of 6.33 (5.65-7.09) and a notably increased risk persisted with hazard ratios of 2.47 (2.04-3.00) for the second and 2.12 (1.71-2.62) for the third year after infection. The risk attenuated with time, but remained raised for at least five years after infection; 1.87 (1.47-2.38). The results are adjusted for characteristics in childhood, cardiovascular risk factors and medical history in adolescence. Similar statistically significant associations were found for coronary heart disease and stroke.Conclusions: Raised risks of cardiovascular disease following hospital admission for sepsis or pneumonia were increased for more than five years after the infection, but with the highest magnitude during the first three years following infection, suggesting a period of vulnerability when health professionals and patients should be aware of the heightened risk for cardiovascular disease. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
653 | a Adult infection | |
653 | a cardiovascular disease | |
653 | a risk factors | |
653 | a sepsis | |
653 | a stroke pneumonia | |
700 | 1 | a Fall, Katja,d 1971-u Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)kafl |
700 | 1 | a Udumyan, Ruzan,d 1971-u Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)run |
700 | 1 | a Sjöqvist, Hugo,d 1992-u Örebro universitet,Handelshögskolan vid Örebro Universitet,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)host |
700 | 1 | a Fröbert, Ole,d 1964-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology, Faculty of Health and Medical Sciences, Örebro University, Örebro, Sweden4 aut0 (Swepub:oru)oft |
700 | 1 | a Montgomery, Scott,d 1961-u Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden; Department of Epidemiology and Public Health, University College London, London, UK,Clinical Epidemiology and Biostatistics4 aut0 (Swepub:oru)smy |
710 | 2 | a Örebro universitetb Institutionen för medicinska vetenskaper4 org |
773 | 0 | t European Journal of Preventive Cardiologyd : Sage Publicationsg 24:18, s. 1958-1966q 24:18<1958-1966x 2047-4873x 2047-4881 |
856 | 4 | u https://doi.org/10.1177/2047487317724009y Fulltext |
856 | 4 | u https://journals.sagepub.com/doi/pdf/10.1177/2047487317724009 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-59088 |
856 | 4 8 | u https://doi.org/10.1177/2047487317724009 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:137106789 |
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