id:"swepub:oai:DiVA.org:oru-65015"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04180nam a2200397 4500 | |
| 001 | oai:DiVA.org:oru-65015 | |
| 003 | SwePub | |
| 008 | 180215s2018 | |||||||||||000 ||eng| | |
| 020 | a 9789175292373q print | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-650152 URI |
| 040 | a (SwePub)oru | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a vet2 swepub-contenttype |
| 072 | 7 | a dok2 swepub-publicationtype |
| 100 | 1 | a Björkenheim, Anna,d 1980-u Örebro universitet,Institutionen för medicinska vetenskaper4 aut0 (Swepub:oru)anbm |
| 245 | 1 0 | a Catheter ablation for atrial fibrillation :b effects on rhythm, symptoms and health-related quality of life |
| 264 | 1 | a Örebro :b Örebro University,c 2018 |
| 300 | a 92 s. | |
| 338 | a electronic2 rdacarrier | |
| 490 | 0 | a Örebro Studies in Medicine,x 1652-4063 ;v 175 |
| 520 | a Background: AF ablation is an increasingly used treatment in patients with AF to improve patient-reported outcomes (PROs). Atrioventricular junction ablation (AVJA) is a palliative treatment option in therapy refractory AF that improves PROs but renders the patient pacemaker dependent.Aims: To evaluate rhythm control and PROs before and up to two years after AF ablation. To analyze the long-term incidence of and predictors of hospitalization for HF and all-cause mortality in patients who underwent AVJA and right ventricular pacing.Methods and Results: Fifty-four patients underwent AF ablation and both continuous rhythm monitoring via an implantable loop recorder (ILR) and intermittent rhythm monitoring three, six, 12 and 24 months after ablation. 76 % of patients had at least one AF recurrence, of whom 24 % were only detected by ILR. One third of symptom recordings did not show AF. The AF-specific AF6 scores, physician-assessed EHRA symptom class and both SF-36 summary scores all improved significantly from before to two years after ablation. There was a weak correlation between the change in AF6 scores and EHRA class from before to six and 12 months but not to 24 months after ablation. Responders to ablation (AF burden < 0.5 %), reached age- and sex-matched norms in all SF-36 domains, but non-responders only in social functioning and MCS. All AF6 scores showed at least moderate improvement in both responders and non-responders. Higher AF burden was independently associated with poorer PCS and AF6 scores. In 162 patients who underwent AVJA, hospitalization for HF occurred in 20 % of patients (two-year cumula-tive incidence 9.1 %) and 22 % died (two-year cumulative incidence 5.2 %) during a median follow-up of five years. QRS ≥ 120 ms and left atrial diame-ter were independent predictors of hospitalization for HF, and hypertension and previous HF of death.Conclusions: Continuous rhythm monitoring was superior to intermittent monitoring. The AF-specific AF6 was more sensitive to changes related to AF burden after AF ablation than both EHRA class and the SF-36. The long-term hospitalization rate for HF and all-cause mortality was low after AVJA. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Allmänmedicin0 (SwePub)302242 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex General Practice0 (SwePub)302242 hsv//eng |
| 653 | a Atrial fibrillation | |
| 653 | a catheter ablation | |
| 653 | a symptoms | |
| 653 | a quality of life | |
| 700 | 1 | a Poçi, Dritan,c Medicine doktor,d 1969-u Örebro universitet,Institutionen för medicinska vetenskaper4 ths0 (Swepub:oru)dnpi |
| 700 | 1 | a Lane, Deirdre,c Professoru Institute of Cardiovascular Sciences, University of Birmingham4 opn |
| 710 | 2 | a Örebro universitetb Institutionen för medicinska vetenskaper4 org |
| 856 | 4 | u https://oru.diva-portal.org/smash/get/diva2:1182977/PREVIEW01.pngx Previewy preview image |
| 856 | 4 | u https://oru.diva-portal.org/smash/get/diva2:1182977/COVER01.pdfy cover |
| 856 | 4 | u https://oru.diva-portal.org/smash/get/diva2:1182977/SPIKBLAD01.pdfy spikblad |
| 856 | 4 | u https://oru.diva-portal.org/smash/get/diva2:1182977/FULLTEXT01.pdfx primaryx Raw objecty fulltext |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-65015 |
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