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Age at Epstein-Barr virus infection and Epstein-Barr virus nuclear antigen-1 antibodies in Swedish children

Simon, K. Claire (author)
Saghafian-Hedengren, Shanie (author)
Stockholms universitet,Avdelningen för immunologi
Sverremark-Ekström, Eva (author)
Stockholms universitet,Avdelningen för immunologi
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Nilsson, Caroline (author)
Karolinska Institutet
Ascherio, Alberto (author)
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 (creator_code:org_t)
Elsevier BV, 2012
2012
English.
In: Multiple Sclerosis and Related Disorders. - : Elsevier BV. - 2211-0348 .- 2211-0356. ; 1:3, s. 136-138
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • There is strong evidence supporting a role for Epstein-Barr virus (EBV) in the etiopathogenesis of multiple sclerosis (MS). Because of the strong association between antibody (Ab) titer against EBV nuclear antigen 1 (EBNA1) and late age at EBV infection, manifested as infectious mononucleosis (IM), and MS risk, we sought to determine whether age at primary EBV infection was associated with subsequent anti-EBNA1 Ab titer in a longitudinal study of Swedish children with EBV seropositivity and anti-EBNA1 Ab titers measured at ages 2, 5, and 10.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)

Keyword

Multiple sclerosis
Epstein-Barr virus
Anti-EBNA
Infectious mononucleosis
Epidemiology
EBV seroconversion

Publication and Content Type

ref (subject category)
art (subject category)

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