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Internet-based psyc...
Internet-based psychodynamic versus cognitive behaviour therapy for adolescents with depression : study protocol for a non-inferiority randomized controlled trial (the ERiCA study)
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- Mechler, Jakob (author)
- Stockholm University,Stockholms universitet,Klinisk psykologi,Stockholm Univ, Dept Psychol, Stockholm, Sweden
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- Lindqvist, Karin (author)
- Stockholm University,Stockholms universitet,Klinisk psykologi,Stockholm Univ, Dept Psychol, Stockholm, Sweden
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- Carlbring, Per (author)
- Stockholm University,Stockholms universitet,Klinisk psykologi,Stockholm Univ, Dept Psychol, Stockholm, Sweden
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- Lilliengren, Peter, 1972- (author)
- Ersta Sköndal Bräcke högskola,S:t Lukas utbildningsinstitut,Ersta Sköndal Bräcke Univ Coll, Stockholm, Sweden
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- Falkenström, Fredrik (author)
- Linköping University,Linköpings universitet,Linköping Univ, Dept Behav Sci & Learning, Linköping, Sweden,Psykologi,Filosofiska fakulteten
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- Andersson, Gerhard, Fil dr, Med dr, 1966- (author)
- Linköpings universitet,Linköping University,Karolinska Institutet,Linköpings universitet; Karolinska institutet,Linköping Univ, Dept Behav Sci & Learning, Linköping, Sweden; Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden,Psykologi,Filosofiska fakulteten
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- Topooco, Naira (author)
- Linköpings universitet,Linköping University,Palo Alto University,Linköpings universitet; Center for m2Health, USA,Linköping Univ, Dept Behav Sci & Learning, Linköping, Sweden; Ctr M2Hlth, Palo Alto, CA USA,Psykologi,Filosofiska fakulteten
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- Johansson, Robert (author)
- Karolinska Institutet,Stockholm University,Stockholms universitet,Klinisk psykologi,Stockholm Univ, Dept Psychol, Stockholm, Sweden
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- Midgley, Nick (author)
- Anna Freud Centre, United Kingdom; University College London, United Kingdom,University College London,Anna Freud Ctr, Child Attachment & Psychol Therapies Res Unit ChA, London, England; UCL, Dept Clin Educ & Hlth Psychol, London, England
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- Edbrooke-Childs, Julian (author)
- University College London, United Kingdom; Anna Freud National Centre for Children and Families, United Kingdom,Anna Freud Centre, London,UCL, Dept Clin Educ & Hlth Psychol, London, England; Anna Freud Natl Ctr Children & Families, Evidence Based Practice Unit, London, England
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- Dahl, Hanne-Sofie J. (author)
- Vestfold Hospital Trust, Norway; University of Oslo, Norway,University of Oslo,Vestfold Hosp Trust, Tønsberg, Norway; Univ Oslo, Dept Psychol, Oslo, Norway
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- Sandell, Rolf (author)
- Lund University,Lunds universitet,Institutionen för psykologi,Samhällsvetenskapliga institutioner och centrumbildningar,Samhällsvetenskapliga fakulteten,Department of Psychology,Departments of Administrative, Economic and Social Sciences,Faculty of Social Sciences,Lund Univ, Dept Psychol, Lund, Sweden
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- Thorén, Agneta (author)
- Erica Foundation,Ericastiftelsen, Stockholm,Erica Fdn, Stockholm, Sweden
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- Ulberg, Randi (author)
- Uppsala universitet,Uppsala University,University of Oslo, Norway; Uppsala universitet; Diakonhjemmet Hospital, Norway,Institutionen för psykologi,Univ Oslo, Div Mental Hlth & Addict, Oslo, Norway; Diakonhjemmet Hosp, Dept Dept Psychiat Res, Dept Adult Psychiat, Oslo, Norway,Univ Oslo, Norway; Uppsala Univ, Sweden; Diakonhjemmet Hosp, Norway
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- Lindert Bergsten, Katja (author)
- Uppsala University,Uppsala universitet,Institutionen för psykologi,Uppsala Univ, Sweden
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- Philips, Björn (author)
- Stockholm University,Stockholms universitet,Klinisk psykologi,Stockholm Univ, Dept Psychol, Stockholm, Sweden
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(creator_code:org_t)
- 2020-06-29
- 2020
- English.
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In: Trials. - : Springer Science and Business Media LLC. - 1745-6215. ; 21:1
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Abstract
Subject headings
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- Background: Adolescent depression is a common mental health problem and there is an urgent need for effective and accessible treatments. Internet-based interventions solve many obstacles for seeking and receiving treatment, thus increasing access to effective treatments. Internet-based cognitive behavioural therapy (ICBT) for adolescent depression has demonstrated efficacy in previous trials. In order to broaden the range of evidence-based treatments for young people, we evaluated a newly developed affect-focused Internet-based psychodynamic treatment (IPDT) in a previous study with promising results. The purpose of the planned study is to evaluate the efficacy of IPDT for adolescent depression in a non-inferiority trial, comparing it to ICBT.Methods: The study will employ a parallel randomized non-inferiority design (ratio 1:1; n = 270). Eligible participants are adolescents 15–19 years suffering from depression. The primary hypothesis is that IPDT will be non-inferior to ICBT in reducing depressive symptoms from pre-treatment to end of treatment. Secondary research questions include comparing outcomes of IPDT and ICBT regarding anxiety symptoms, emotion regulation and self-compassion. Additional data will be collected to evaluate cost-effectiveness as well as investigating predictors, moderators and mediators of outcome. In addition, we will examine long-term outcome up to 1 year after end of treatment. Diagnostic interviews with MINI 7.0 will be used to establish primary diagnosis of depression as well as ruling out any exclusion criteria. Both treatments consist of eight modules over 10 weeks, complemented with therapist support through text messages and weekly chat sessions. Primary outcome measure is the Quick Inventory of Depressive Symptomatology in Adolescents Self-Rated (QIDS-A17-SR). Primary outcome will be analysed using data from all participants entering the study using a multilevel growth curve strategy based on the weekly measurements of QIDS-A17-SR. The non-inferiority margin is defined as d = 0.30.Discussion: This trial will demonstrate whether IPDT is non-inferior to ICBT in the treatment of adolescent depression. The study might therefore broaden the range of evidence-based treatment alternatives for young people struggling with depression. Further analyses of data from this trial may increase our knowledge about “what works for whom” and the pathways of change for two distinct types of interventions.Trial registration: ISRCTN12552584, Registered on 13 August 2019.
Subject headings
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
- SAMHÄLLSVETENSKAP -- Psykologi -- Tillämpad psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology -- Applied Psychology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- depression
- non-inferiority trial
- adolescents
- psychodynamic
- CBT
- internet-based treatment
- Psychology
- psykologi
- Adolescents
- CBT
- Depression
- Internet-based treatment
- Non-inferiority trial
- Psychodynamic
Publication and Content Type
- ref (subject category)
- art (subject category)
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Trials
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- By the author/editor
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Mechler, Jakob
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Lindqvist, Karin
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Carlbring, Per
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Lilliengren, Pet ...
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Falkenström, Fre ...
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Andersson, Gerha ...
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show more...
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Topooco, Naira
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Johansson, Rober ...
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Midgley, Nick
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Edbrooke-Childs, ...
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Dahl, Hanne-Sofi ...
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Sandell, Rolf
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Thorén, Agneta
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Ulberg, Randi
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Lindert Bergsten ...
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Philips, Björn
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- About the subject
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Psychology
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Psychology
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and Applied Psycholo ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Psychiatry
- Articles in the publication
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Trials
- By the university
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Stockholm University
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Lund University
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Karolinska Institutet
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Marie Cederschiöld högskola
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Uppsala University
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Linköping University