SYNTHESIS, ANTIMICROBIAL ACTIVITY, UREASE INHIBITION AND MOLECULAR DOCKING STUDIES OF NEW PROLINE LINKED THIOUREA DERIVATIVES

Raheel, Ahmad (author)

Iftikhar, Syed Hassan (author)

Taj, Muhammad Babar (author)

Ayub, Rabia (author): Stockholms universitet,Institutionen för organisk kemi

Zafar, Anham (author)

Abbas, Sumaira (author)

Al-Shakban, Mundher (author)

(creator_code:org_t)

2020
2020
English.
In: Revue roumaine de chimie. - : Romanian Academy - Revue Roumaine De Chimie. - 0035-3930. ; 65:9, s. 783-788

Related links:: https://doi.org/10.3...; show more...; https://doi.org/10.3...; https://urn.kb.se/re...; https://doi.org/10.3...; show less...

Abstract Subject headings

A series of new thiourea based carboxylic acids (I-a-I-e) were synthesized and characterized by elemental analysis, FTIR and NMR (H-1 and C-13) spectroscopy. They were preliminary bioassayed for their antibacterial, anifungal and urease inhibition activities. Molecular docking simulations were carried out to determine the probable binding mode of the synthesized compounds. The bioassay results showed that some of titled compounds exhibited encouraging results.

By the author/editor: Raheel, Ahmad; Iftikhar, Syed H ...; Taj, Muhammad Ba ...; Ayub, Rabia; Zafar, Anham; Abbas, Sumaira; show more...; Al-Shakban, Mund ...; show less...

About the subject

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