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Polyfluoroalkyl pho...
Polyfluoroalkyl phosphate esters and perfluoroalkyl carboxylic acids in target food samples and packaging - method development and screening
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- Gebbink, Wouter A. (författare)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
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- Ullah, Shahid, 1977- (författare)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
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- Sandblom, Oskar (författare)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
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- Berger, Urs (författare)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
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(creator_code:org_t)
- 2013-03-15
- 2013
- Engelska.
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Ingår i: Environmental Science and Pollution Research. - : Springer Science and Business Media LLC. - 0944-1344 .- 1614-7499. ; 20:11, s. 7949-7958
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Polyfluoroalkyl phosphate mono-, di-, and tri-esters (mono-, di-, and triPAPs) are used to water- and grease-proof food packaging materials, and these chemicals are known precursors to perfluoroalkyl carboxylic acids (PFCAs). Existing analytical methods for PAPs lack sample clean-up steps in the sample preparation. In the present study, a method based on ultra performance liquid chromatography coupled to tandem mass spectrometry (UPLC/MS/MS) was developed and optimized for the analysis of mono-, di-, and triPAPs, including a clean-up step for the raw extracts. The method was applied to food samples and their PAP-containing packaging materials. The optimized UPLC/MS/MS method enabled the separation and identification of a total of 4 monoPAPs, 16 diPAPs, and 7 triPAPs in the technical mixture Zonyl®-RP. For sample clean-up, weak anion exchange solid phase extraction columns were tested. PAPs standard solutions spiked onto the columns were separated into a fraction containing neutral compounds (triPAPs) and a fraction with ionic compounds (mono- and diPAPs) with recoveries between 72–110 %. Method limits of quantification for food samples were in the sub to low picogram per gram range. For quantitative analysis of PAPs, compound-specific labeled internal standards showed to be essential as sorption and matrix effects were observed. Mono-, di-, and/or triPAPs were detected in all food packaging materials obtained from the Swedish market. Up to nine diPAPs were detected in the food samples, with the 6:2/6:2 and 6:2/8:2 diPAPs as the dominant compounds. DiPAP concentrations in the food samples ranged from 0.9 to 36 pg/g, which was comparable to individual PFCA concentrations in the same samples. Consumption of food packed in PAP-containing materials could be an indirect source of human exposure to PFCAs.
Ämnesord
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
Nyckelord
- PAPs
- FOOD
- Precursor
- PFCAs
- method development
- LC-MSMS
- Applied Environmental Science
- tillämpad miljövetenskap
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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