id:"swepub:oai:DiVA.org:umu-107080"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03716naa a2200409 4500 | |
| 001 | oai:DiVA.org:umu-107080 | |
| 003 | SwePub | |
| 008 | 150818s2015 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1070802 URI |
| 024 | 7 | a https://doi.org/10.1111/imj.127842 DOI |
| 040 | a (SwePub)umu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Ahangari, Alebtekinu Umeå universitet,Obstetrik och gynekologi,Umeå Neurosteroid Research Center, Umeå University, Umeå, Sweden4 aut0 (Swepub:umu)alah0014 |
| 245 | 1 0 | a Acute intermittent porphyria symptoms during the menstrual cycle |
| 264 | c 2015-07-01 | |
| 264 | 1 | b Wiley,c 2015 |
| 338 | a print2 rdacarrier | |
| 520 | a Background: Acute intermittent porphyria (AIP), a life-threatening form of the disease, is accompanied by several pain, mental and physical symptoms.Aims: In this study, we evaluated the cyclicity of AIP and premenstrual syndrome (PMS) symptoms in 32 women with DNA-diagnosed AIP during their menstrual cycles, in northern Sweden.Methods: The cyclicity of AIP symptoms and differences in them between the follicularand luteal phases, and the cyclicity of each symptom in each individual woman indifferent phases of her menstrual cycle were analysed with a prospective daily ratingquestionnaire. PMS symptoms were also evaluated in the patients on a daily rating scale.Results: Of the 32 women, 30 showed significant cyclicity in at least one AIP or PMS symptom (P < 0.05–0.001). Back pain (10/32) was the most frequent AIP pain symptomand sweet craving (10/15) was the most frequent PMS symptom. Pelvic pain (F = 4.823,P = 0.036), irritability (F = 7.399, P = 0.011), cheerfulness (F = 5.563, P = 0.025), sexualdesire (F = 8.298, P = 0.007), friendliness (F = 6.157, P = 0.019), breast tenderness (F =21.888, P = 0.000) and abdominal swelling (F = 16.982, P = 0.000) showed significantcyclicity. Pelvic pain and abdominal swelling (rs= 0.337, P < 0.001) showed the strongest correlation. The age of women with latent AIP was strongly correlated with abdominal swelling during the luteal phase (rs= 0.493, P < 0.01).Conclusion: Our results suggest that the symptoms of AIP patients change during their menstrual cycles. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Reproduktionsmedicin och gynekologi0 (SwePub)302202 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Obstetrics, Gynaecology and Reproductive Medicine0 (SwePub)302202 hsv//eng |
| 653 | a acute intermittent porphyria | |
| 653 | a PMS/PMDD | |
| 653 | a progesterone | |
| 653 | a pain | |
| 653 | a hormone | |
| 653 | a symptomcyclicity | |
| 700 | 1 | a Bäckström, Torbjörnu Umeå universitet,Obstetrik och gynekologi,Umeå Neurosteroid Research Center, Umeå University, Umeå, Sweden4 aut0 (Swepub:umu)toba0001 |
| 700 | 1 | a Innala, Evau Umeå universitet,Obstetrik och gynekologi,Umeå Neurosteroid Research Center, Umeå University, Umeå, Sweden4 aut0 (Swepub:umu)evin0004 |
| 700 | 1 | a Andersson, C.u Umeå universitet,Obstetrik och gynekologi,Umeå Neurosteroid Research Center, Umeå University, Umeå, Sweden4 aut |
| 700 | 1 | a Turkmen, Sahruhu Umeå universitet,Obstetrik och gynekologi,Umeå Neurosteroid Research Center, Umeå University, Umeå, Sweden4 aut0 (Swepub:umu)satu0001 |
| 710 | 2 | a Umeå universitetb Obstetrik och gynekologi4 org |
| 773 | 0 | t Internal medicine journal (Print)d : Wileyg 45:7, s. 725-731q 45:7<725-731x 1444-0903x 1445-5994 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-107080 |
| 856 | 4 8 | u https://doi.org/10.1111/imj.12784 |
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