id:"swepub:oai:DiVA.org:umu-110768"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 02743naa a2200409 4500 | |
| 001 | oai:DiVA.org:umu-110768 | |
| 003 | SwePub | |
| 008 | 151028s2005 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:1953249 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1107682 URI |
| 024 | 7 | a https://doi.org/10.1111/j.0022-202X.2004.23501.x2 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19532492 URI |
| 040 | a (SwePub)umud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Carlén, Lina M4 aut |
| 245 | 1 0 | a Proteome analysis of skin distinguishes acute guttate from chronic plaque psoriasis. |
| 264 | 1 | c 2005 |
| 338 | a print2 rdacarrier | |
| 520 | a Psoriasis is a disease with considerable heterogeneity in clinical presentation. This is the first study using two-dimensional gel electrophoresis to compare global protein expression patterns in lesional and non-lesional skin from subjects with acute guttate psoriasis associated with streptococcal throat infection and chronic plaque psoriasis. Samples from experimentally induced contact eczema and normal skin from healthy controls were also included. Proteins with statistically significant differences in expression were used in hierarchical cluster analyses resulting in separation of the different samples into groups. Chronic plaque and guttate psoriasis samples were distinctly separated, indicating that they represent discrete phenotypes at the protein expression level. Interestingly, there was a trend in which guttate psoriasis lesions clustered closer to eczema than to chronic plaque psoriasis lesions, indicating that the duration of the inflammatory reaction may affect clustering. Several of the differentially expressed proteins were identified by mass spectrometry. | |
| 700 | 1 | a Sánchez, Fabiou Karolinska Institutet4 aut |
| 700 | 1 | a Bergman, Ann-Charlotteu Karolinska Institutet4 aut |
| 700 | 1 | a Becker, Susanne4 aut |
| 700 | 1 | a Hirschberg, Daniel4 aut |
| 700 | 1 | a Franzén, Bou Karolinska Institutet4 aut |
| 700 | 1 | a Coffey, Jonathan4 aut |
| 700 | 1 | a Jörnvall, Hansu Karolinska Institutet4 aut |
| 700 | 1 | a Auer, Gertu Karolinska Institutet4 aut |
| 700 | 1 | a Alaiya, Ayodele A4 aut |
| 700 | 1 | a Ståhle, Monau Karolinska Institutet4 aut |
| 710 | 2 | a Karolinska Institutet4 org |
| 773 | 0 | t Journal of Investigative Dermatologyg 124:1q 124:1x 0022-202Xx 1523-1747 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-110768 |
| 856 | 4 8 | u https://doi.org/10.1111/j.0022-202X.2004.23501.x |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1953249 |
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