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Two Cases of LQT Syndrome with Malignant Syncope after Switch from Propranolol to Bisoprolol
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- Kesek, Milos (author)
- Umeå universitet,Kardiologi
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- Rydberg, Annika (author)
- Umeå universitet,Pediatrik
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- Jensen, Steen M (author)
- Umeå universitet,Kardiologi
- (creator_code:org_t)
- 2015-12-03
- 2016
- English.
- In: Pacing and Clinical Electrophysiology. - : Wiley. - 0147-8389 .- 1540-8159. ; 39:3, s. 305-306
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Propranolol in slow-release form has been the first-line treatment in long QT (LQT) until it was withdrawn from the market. We describe two cases where a switch to bisoprolol resulted in worsening of arrhythmia control: A man with LQT2, asymptomatic on propranolol, experienced syncope after switching to bisoprolol 5 mg daily. He switched back to propranolol and has remained asymptomatic during subsequent 12 months. A man with classical Jervell Lange-Nielsen syndrome, previous gangliectomy, and ICD implantation, switched to bisoprolol 5 mg daily. Four months later he experienced a tachycardia storm. He switched back to propranolol and has remained free from arrhythmias during subsequent 12 months.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- long QT
- pharmacology
- beta-blocker therapy
- bisoprolol
- propranolol
Publication and Content Type
- ref (subject category)
- art (subject category)
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