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Time trends in T3 t...
Time trends in T3 to T4 laryngeal cancer : a population-based long-term analysis.
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Reizenstein, Johan A (author)
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- Holmberg, Lars (author)
- Regional Cancer Centre, Uppsala, Sweden
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- Bergqvist, Michael (author)
- Uppsala universitet,Enheten för onkologi
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- Linder, Arne (author)
- Uppsala universitet,Öron-, näs- och halssjukdomar
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- Ekman, Simon (author)
- Uppsala universitet,Enheten för onkologi
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Lödén, Britta (author)
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- Holmqvist, Marit (author)
- Regional Cancer Centre, Uppsala, Sweden
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Hellström, Karin (author)
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von Beckerath, Mattias (author)
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- Blomquist, Erik (author)
- Uppsala universitet,Enheten för onkologi
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Bergström, Stefan N (author)
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(creator_code:org_t)
- 2014-01-29
- 2014
- English.
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In: Head and Neck. - : Wiley. - 1043-3074 .- 1097-0347. ; 36:12
- Related links:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
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- BACKGROUND: A decline in laryngectomies and survival in laryngeal cancer has been reported, especially among patients with advanced tumors.METHODS: Of 1058 patients with laryngeal cancer diagnosed from 1978 to 2007 in the Uppsala-Örebro region in Sweden, 263 T3 to T4 tumors treated with curative intent were studied retrospectively. Two time periods were defined, 1978 to 1992 and 1993 to 2007.RESULTS: Glottic tumors decreased constituting 68.6% of cases in 1978 to 1992 and 47.9% in 1993 to 2007. Laryngectomies were performed in 38.8% and 34.5% in the corresponding time periods. The use of laryngectomy was not strongly prognostic. A decline in overall survival (OS) over time could only be identified for the first year of follow-up. Chemotherapy was only used in a minority of cases.CONCLUSION: The marked decrease of glottic site may mark a shift in etiology. Laryngectomy was not strongly associated with improved survival. The absence of improved survival calls for intensified research.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Reizenstein, Joh ...
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Holmberg, Lars
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Bergqvist, Micha ...
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Linder, Arne
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Ekman, Simon
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Lödén, Britta
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show more...
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Holmqvist, Marit
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Hellström, Karin
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von Beckerath, M ...
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Blomquist, Erik
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Bergström, Stefa ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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Head and Neck
- By the university
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Umeå University
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Uppsala University