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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003968naa a2200481 4500
001oai:DiVA.org:umu-128593
003SwePub
008161207s2016 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1285932 URI
024a https://doi.org/10.3748/wjg.v22.i38.85402 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Karling, Pontusu Umeå universitet,Medicin4 aut0 (Swepub:umu)peakag84
2451 0a Association between gastrointestinal symptoms and affectivity in patients with bipolar disorder
264 1b Baishideng,c 2016
338 a electronic2 rdacarrier
520 a AIM: To study if anxiety, depression and experience of stress are associated with gastrointestinal (GI) symptoms in patients with bipolar disorder.METHODS: A total of 136 patients with bipolar disorder (mean age 49.9 years; 61% women) and 136 controls from the general population (mean age 51.0 years; 60% women) were included in the study. GI symptoms were assessed with The Gastrointestinal Symptom Rating Scale-irritable bowel syndrome (GSRS-IBS), level of anxiety and depression with The Hospital Anxiety and Depression Scale (HADS) and stress-proneness with Perceived Stress Questionnaire. Over a ten year period, all visits in primary care were retrospectively recorded in order to identify functional GI disorders.RESULTS: In subjects with low total HADS-score, there were no significant differences in GI-symptoms between patients and controls (GSRS-IBS 7.0 vs 6.5, P = 0.513). In the patients with bipolar disorder there were significant correlations between all GSRS and HADS subscores for all symptom clusters except for "constipation" and "reflux". Factors associated to GI symptoms in the patient group were female sex (adjusted OR = 2.37, 95%CI: 1.07-5.24) and high HADS-Depression score (adjusted OR = 3.64, 95%CI: 1.07-12.4). These patients had also significantly more visits for IBS than patients with low HADS-Depression scores (29% vs 8%, P = 0.008). However, there was no significant differences in consulting behaviour for functional GI disorders between patients and controls (25% vs 17%, P = 0.108).CONCLUSION: Female patients and patients with high HADS depression score reported significantly more GI symptoms, whereas patients with low HADS scores did not differ from control subjects.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Gastroenterologi0 (SwePub)302132 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Gastroenterology and Hepatology0 (SwePub)302132 hsv//eng
653 a Anxiety
653 a Bipolar disorder
653 a Brain-Gut axis
653 a Depression
653 a Dyspepsia
653 a Functional gastrointestinal disorder
653 a Gastrointestinal Symptom Rating Scale- irritable bowel syndrome
653 a Irritable bowel syndrome
653 a Hospital Anxiety and Depression Scale
653 a Stress
700a Maripuu, Martinu Umeå universitet,Psykiatri4 aut0 (Swepub:umu)manmau98
700a Wikgren, Mikaelu Umeå universitet,Psykiatri4 aut0 (Swepub:umu)penmel02
700a Adolfsson, Rolfu Umeå universitet,Psykiatri4 aut0 (Swepub:umu)road0001
700a Norrback, Karl-Fredriku Umeå universitet,Psykiatri4 aut0 (Swepub:umu)kaknok96
710a Umeå universitetb Medicin4 org
773t World Journal of Gastroenterologyd : Baishidengg 22:38, s. 8540-8548q 22:38<8540-8548x 1007-9327x 2219-2840
856u https://doi.org/10.3748/wjg.v22.i38.8540y Fulltext
856u https://umu.diva-portal.org/smash/get/diva2:1052886/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856u https://europepmc.org/articles/pmc5064035?pdf=render
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-128593
8564 8u https://doi.org/10.3748/wjg.v22.i38.8540

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