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C-11-Acetate-PET/CT...
C-11-Acetate-PET/CT Compared to Tc-99m-HDP Bone Scintigraphy in Primary Staging of High-risk Prostate Cancer
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- Strandberg, Sara (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper
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- Karlsson, Camilla Thellenberg (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper
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- Ögren, Mattias (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper
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- Axelsson, Jan (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper
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- Riklund, Katrine (författare)
- Umeå universitet,Institutionen för strålningsvetenskaper
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(creator_code:org_t)
- International Institute of Anticancer Research, 2016
- 2016
- Engelska.
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Ingår i: Anticancer Research. - : International Institute of Anticancer Research. - 0250-7005 .- 1791-7530. ; 36:12, s. 6475-6479
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- Aim: The aim of this study was to evaluate the detection rate of bone metastases and the added value of C-11-acetate (ACE) positron-emission tomography/computed tomography (PET/CT) compared to bone scintigraphy (BS) in high-risk prostate cancer (PC).Materials and Methods: A total of 66 untreated patients with high-risk PC with ACE-PET/CT and planar BS findings within 3 months of each other were retrospectively enrolled. Findings were compared and verified with follow-up data after an average of 26 months.Results: The rate of detection of bone metastases was superior with ACE-PET/CT compared to BS (p<0.01). Agreement between the methods and between BS and follow-up was moderate (Cohen's kappa coefficient of 0.64 and 0.66, respectively). Agreement between ACE-PET/CT and follow-up was excellent (kappa coefficient of 0.95). Therapy was changed in 11% of patients due to ACE-PET/CT results.Conclusion: ACE-PET/CT performed better than planar BS in detection of bone metastases in high-risk PC. ACE-PET/CT findings influenced clinical management.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Prostate cancer
- PET/CT
- [C-11]-acetate
- bone scintigraphy
- bone metastasis
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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