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Residues determining the binding specificity of uncompetitive inhibitors to tissue-nonspecific alkaline phosphatase.

Kozlenkov, Alexey (author)
Umeå universitet,Medicinsk och klinisk genetik
Le Du, Marie Helene (author)
Cuniasse, Philippe (author)
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Ny, Tor (author)
Umeå universitet,Institutionen för medicinsk kemi och biofysik
Hoylaerts, Marc F (author)
Millán, José Luis (author)
Umeå universitet,Medicinsk och klinisk genetik
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 (creator_code:org_t)
2004
2004
English.
In: Journal of bone and mineral research. - 0884-0431. ; 19:11, s. 1862-72
  • Journal article (peer-reviewed)
Subject headings
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Keyword

Alkaline Phosphatase/*chemistry/genetics/metabolism
Animals
Binding Sites
Binding; Competitive
Bone and Bones/physiology
Drug Design
Enzyme Inhibitors/pharmacology
Homoarginine/pharmacology
Humans
Kinetics
Levamisole/pharmacology
Mice
Mice; Transgenic
Models; Chemical
Models; Molecular
Models; Theoretical
Mutagenesis
Mutagenesis; Site-Directed
Mutation
Phenylalanine/pharmacology
Placenta/enzymology
Protein Binding
Protein Isoforms
Software
Theophylline/pharmacology

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ref (subject category)
art (subject category)

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