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Quality of life after end colostomy without mesh and with prophylactic synthetic mesh in sublay position : one-year results of the STOMAMESH trial
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- Näverlo, Simon (author)
- Umeå universitet,Kirurgi
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- Gunnarsson, Ulf (author)
- Umeå universitet,Kirurgi
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- Strigård, Karin (author)
- Umeå universitet,Kirurgi
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- (creator_code:org_t)
- 2019-08-07
- 2019
- English.
- In: International Journal of Colorectal Disease. - : Springer. - 0179-1958 .- 1432-1262. ; 34:9, s. 1591-1599
- Journal article (peer-reviewed)
Abstract
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- Purpose: To determine whether prophylactic mesh in a sublay position has an impact on the quality-of-life (QoL) of patients receiving an end colostomy.Methods: One-year follow-up of patients from the STOMAMESH trial, a randomized controlled double-blinded multicenter study. Patients were randomized to either prophylactic synthetic mesh with a cruciform incision in the center, placed in sublay position, or no prophylactic mesh. Patients attended a 1-year visit and responded to the questionnaires EORTC QLQ C-30 and CR-38. The impact of having a mesh on QoL was determined by comparing a group of patients receiving a mesh with a group without. A subgroup analysis was made depending on whether a PSH was clinically present or not.Results: Of the 232 randomized patients, 211 patients reached the 1-year clinical follow-up. The response rate of these 211 patients was 70%. No differences were seen in global QoL between the groups. Mesh patients reported significantly less stoma-related problems (p = 0.014) but more sexual problems in males (p = 0.022). When excluding patients with a clinical diagnosis of PSH, the difference in stoma-related problems remained while no significant difference was seen regarding sexual problems in males.Conclusions: When forming an end colostomy, prophylactic synthetic mesh in a sublay position did not affect global QoL at 1-year follow-up, but stoma-related problems were fewer even in the presence of a clinically diagnosed PSH.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- Quality-of-life
- Mesh
- Parastomal hernia
- Prophylaxis
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Näverlo, Simon
- Gunnarsson, Ulf
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- Näsvall, Pia
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