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Sökning: id:"swepub:oai:DiVA.org:umu-180233" > Age at asthma diagn...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003673naa a2200481 4500
001oai:DiVA.org:umu-180233
003SwePub
008210219s2020 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1802332 URI
0247 a https://doi.org/10.1183/13993003.congress-2020.46412 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a vet2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Honkamaki, Jasmin4 aut
2451 0a Age at asthma diagnosis and probability of remission in a population-based study
264 c 2020-10-28
264 1b ERS Publications,c 2020
338 a print2 rdacarrier
520 a Background: Child-onset asthma is known to remit with high probability but remission in adult-onset asthma seems to be less common. Reports of association between remission and asthma onset age in adulthood are scarce.Objectives: To study if age at asthma diagnosis and gender are associated to remission rate in adult asthma population.Methods: In 2016, a random sample of 16 000 subjects aged 20-69 years from Helsinki and Western Finland were sent a FinEsS-questionnaire. Asthma was categorized by reported age when diagnosed with asthma by a physician: child (0-11 years) adolescent-young-adult (12-39 years) and late-adult-diagnosed (40-69 years). Remission was defined as a physician diagnosed asthma but not having had asthma symptoms, wheezing or use of asthma medication in the past 12 months.Results: 8199 subjects (51.5%) responded to the postal questionnaire. Remission was most common in child-diagnosed (30.2%), followed by adolescent-young-adult-diagnosed (17.9%) and least common in late-adult-diagnosed asthma (5.0%) (p<0.001). In males, the corresponding proportions were 36.7%, 20.0% and 3.4%, and in females 20.4%, 16.6% and 5.9%, respectively (p<0.001 for gender difference). In binary logistic regression, significant risk factors of non-remission were diagnosis at adolescent-young-adulthood- (OR=2.2, 95% CI 1.4-3.4) or late-adulthood- (OR=11.1, 4.8-25.4), asthma-COPD overlap (ACO) (OR=5.6, 1.3-24.5), allergic rhinitis (OR=2.3, 1.5-3.5) and family history of asthma (OR=1.9, 1.2-2.8). Results remained similar after exclusion of ACO.Conclusion: Remission was rare (5%) in adults diagnosed with asthma after age 40 years in both sexes. Causes of poor prognosis in adult-onset asthma need to be further elucidated.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng
653 a Asthma
653 a Adults
653 a Adolescents
7001 a Piirila, Paivi4 aut
7001 a Hisinger-Molkanen, Hanna4 aut
7001 a Tuomisto, Leena E.4 aut
7001 a Andersen, Heidi4 aut
7001 a Huhtala, Heini4 aut
7001 a Sovijarvi, Anssi4 aut
7001 a Backman, Helenau Umeå universitet,Institutionen för folkhälsa och klinisk medicin4 aut0 (Swepub:umu)heaban01
7001 a Lundback, Bo4 aut
7001 a Ronmark, Eva4 aut
7001 a Lehtimaki, Lauri4 aut
7001 a Pallasaho, Paula4 aut
7001 a Ilmarinen, Pinja4 aut
7001 a Kankaanranta, Hannu4 aut
7102 a Umeå universitetb Institutionen för folkhälsa och klinisk medicin4 org
7730 t European Respiratory Journald : ERS Publicationsg 56:Suppl 64q 56:Suppl 64x 0903-1936x 1399-3003
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-180233
8564 8u https://doi.org/10.1183/13993003.congress-2020.4641

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