id:"swepub:oai:DiVA.org:umu-183567"
Search: id:"swepub:oai:DiVA.org:umu-183567" > The utility of lung...
- 1 of 1
- Previous record
- Next record
- To hitlist
The utility of lung weight to heart weight ratio as a means to identify suspected drug intoxication deaths in a medico-legal autopsy population
-
- Gustafsson, Torfinn (author)
- Umeå University,Umeå universitet,Rättsmedicin,The National Board of Forensic Medicine, Stockholm, Sweden,Swedish National Board of Forensic Medicine, Stockholm
-
- Eriksson, Anders (author)
- Umeå University,Umeå universitet,Rättsmedicin
-
- Wingren, Carl Johan (author)
- Lund University,Lunds universitet,Rättsmedicin,Forskargrupper vid Lunds universitet,Forensic Medicine,Lund University Research Groups,Swedish National Board of Forensic Medicine, Stockholm
- (creator_code:org_t)
- 2021-05-06
- 2021
- English.
- In: Journal of Forensic Sciences. - : John Wiley & Sons. - 0022-1198 .- 1556-4029. ; 66:4, s. 1329-1333
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Fatal intoxications are common in a medico-legal autopsy setting and are associated with sparse findings during autopsy. It has been suggested that an increased lung weight may be associated with such fatalities. Previous literature is generally limited to a descriptive approach, including only opioid deaths, and lacking a definition of “heavy” lungs. Our aim was to create a model to identify cases with heavy lungs and to assess the predictive power of “heavy” lungs in identifying cases of different types of fatal intoxications during autopsy in an unselected medico-legal autopsy population. We identified all medico-legal autopsy cases ≥18 years in Sweden from 2000 through 2013. The lung weight to heart weight (LWHW) ratio was calculated. The positive predictive values (PPV) and negative predictive values (NPV) of both lung weight and LWHW ratio were calculated. Mean lung weight was higher in the intoxication group but the predictive power in the individual case was limited. Lung weight to heart weight ratio had better predictive power than lung weight alone, with a PPV of at most 0.15(0.14, 0.16 95% CI), while the NPV was 0.96 (0.95, 0.96 95% CI). The association between fatal intoxication and increased lung weight was positive, regardless of method and cutoffs used. While the PPV was poor, the NPV could reduce suspicion of fatal intoxication in the absence of other information. LHWH ratio is only a probability factor for fatal intoxication; accurate cause of death determination—as always—requires consideration of circumstances, autopsy, and toxicologic findings.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Rättsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Forensic Science (hsv//eng)
Keyword
- autopsy
- fatal Intoxication
- forensic pathology
- lung weight
- lung: heart weight ratio
- opioid
- predictive value
- autopsy
- fatal Intoxication
- forensic pathology
- lung weight
- lung: heart weight ratio
- opioid
- predictive value
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Journal of Forensic Sciences (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Gustafsson, Torf ...
- Eriksson, Anders
- Wingren, Carl Jo ...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Other Medical an ...
- and Forensic Science
- Articles in the publication
- Journal of Foren ...
- By the university
- Umeå University
- Lund University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
