White matter microstructure and volume correlates of premenstrual dysphoric disorder

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: id:"swepub:oai:DiVA.org:umu-192888" > White matter micros...

1 of 1
Previous record
Next record
To hitlist

White matter microstructure and volume correlates of premenstrual dysphoric disorder

Gu, Xuan (author): Uppsala universitet,Science for Life Laboratory, SciLifeLab,Institutionen för neurovetenskap

Dubol, Manon (author): Uppsala universitet,Science for Life Laboratory, SciLifeLab

Stiernman, Louise (author): Umeå universitet,Obstetrik och gynekologi,Umeå Univ, Dept Clin Sci, Umeå, Sweden.

Wikström, Johan, 1964- (author): Uppsala universitet,Radiologi

Hahn, Andreas (author): Department of Psychiatry and Psychotherapy, Medical University of Vienna, Austria,Med Univ Vienna, Dept Psychiat & Psychotherapy, Vienna, Austria.

Lanzenberger, Rupert (author): Department of Psychiatry and Psychotherapy, Medical University of Vienna, Austria,Med Univ Vienna, Dept Psychiat & Psychotherapy, Vienna, Austria.

Epperson, C. Neill (author): Department of Psychiatry, University of Colorado School of Medicine, USA,Univ Colorado, Sch Med, Dept Psychiat, Boulder, CO 80309 USA.

Bixo, Marie (author): Umeå universitet,Obstetrik och gynekologi,Umeå Univ, Dept Clin Sci, Umeå, Sweden.

Sundström Poromaa, Inger, 1964- (author): Uppsala universitet,Reproduktiv hälsa

Comasco, Erika, 1982- (author): Uppsala universitet,Reproduktiv hälsa,Science for Life Laboratory, SciLifeLab

show less...

(creator_code:org_t)

2022-02-23
2022
English.
In: Journal of Psychiatry & Neuroscience. - : Canadian Medical Association. - 1180-4882 .- 1488-2434. ; 47:1, s. E67-E76

Related links:: https://doi.org/10.1...; show more...; https://umu.diva-por... (primary) (Raw object); https://www.jpn.ca/c...; https://uu.diva-port... (primary) (Raw object); https://urn.kb.se/re...; https://doi.org/10.1...; https://urn.kb.se/re...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

BACKGROUND: Premenstrual dysphoric disorder (PMDD) is a mood disorder characterized by psychological and physical symptoms. Differences in white matter have been associated with affective and anxiety disorders, which share some symptoms with PMDD. However, whether white matter structure differs between the brains of individuals with PMDD and healthy controls is not known, nor is its relation to symptom severity.METHODS: We performed tract-based spatial statistics and voxel-based morphometry analyses of diffusion tensor imaging metrics and white matter volume, using 2 neuroimaging data sets (n = 67 and n = 131) and a combined whole-brain and region-of-interest approach. We performed correlation analyses to investigate the relationship between regions with different white matter microstructure and volume and PMDD symptom severity.RESULTS: We found greater fractional anisotropy in the left uncinate fasciculus (d = 0.69) in individuals with PMDD compared to controls. Moreover, the volume of the right uncinate fasciculus was higher in individuals with PMDD compared to controls (d = 0.40). As well, the severity of premenstrual depression was positively correlated with fractional anisotropy in the right superior longitudinal fasciculus (r = 0.35).LIMITATIONS: It is challenging to interpret group differences in diffusion tensor imaging metrics in terms of their underlying biophysical properties. The small size of the control group in the diffusion tensor imaging study may have prevented effects of interest from being detected.CONCLUSION: The findings of the present study provide evidence of differential cerebral white matter structure associated with PMDD and its symptoms.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)

Publication and Content Type

ref (subject category)
art (subject category)

Find in a library

Journal of Psychiatry & Neuroscience (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Gu, Xuan; Dubol, Manon; Stiernman, Louis ...; Wikström, Johan, ...; Hahn, Andreas; Lanzenberger, Ru ...; show more...; Epperson, C. Nei ...; Bixo, Marie; Sundström Poroma ...; Comasco, Erika, ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Psychiatry

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Neurosciences

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Radiology Nuclea ...

Articles in the publication: Journal of Psych ...

By the university: Umeå University; Uppsala University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se