Search: id:"swepub:oai:DiVA.org:umu-19330" >
Effect of intensive...
Effect of intensive lifestyle intervention on C-reactive protein in subjects with impaired glucose tolerance and obesity : results from a randomized controlled trial with 5-year follow-up
-
- Andersson, Jonas, 1977- (author)
- Umeå universitet,Medicin
-
- Boman, Kurt (author)
- Umeå universitet,Medicin
-
- Jansson, Jan-Håkan (author)
- Umeå universitet,Medicin
-
show more...
-
Nilsson, Torbjørn K (author)
-
- Lindahl, Bernt (author)
- Umeå universitet,Yrkes- och miljömedicin
-
show less...
-
(creator_code:org_t)
- 2009-01-08
- 2008
- English.
-
In: Biomarkers: biochemical indicators of exposure, response, and susceptibility to chemicals. - : Informa UK Limited. - 1366-5804. ; 13:7, s. 671-679
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- C-reactive protein (CRP) is a marker of metabolic and cardiovascular disease. To study the effects of lifestyle on CRP in a high-risk population we conducted a randomized controlled trial on 200 obese subjects (BMI > 27 kg m(-2)) with impaired glucose tolerance recruited from primary care settings. They were randomized to either a 1-month stay at a wellness centre focusing on diet, exercise and stress management (intervention group) or 30-60 min of oral and written information on lifestyle intervention (control group). A significant reduction of CRP was observed after 1 month and 1 year in the intervention group. They reduced their CRP levels more than the control group 1 year after intervention (p=0.004). In conclusion lifestyle intervention can decrease CRP in obese individuals with impaired glucose tolerance for up to 1 year. Further research is needed to evaluate whether the CRP level reduction translates into a decreased risk for cardiovascular morbidity.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Internal medicine
- Invärtesmedicin
- medicin
- Medicine
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database