Severe Preeclampsia With and Without HELLP Differ With Regard to Placental Pathology

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: id:"swepub:oai:DiVA.org:umu-195269" > Severe Preeclampsia...

1 of 1
Previous record
Next record
To hitlist

Severe Preeclampsia With and Without HELLP Differ With Regard to Placental Pathology

Vinnars, Marie-Therese (author): Department of Laboratory Medicine, Division of Pathology, and Department of Obstetrics and Gynecology, CLINTEC, Karolinska Institutet, Stockholm, Sweden

Wijnaendts, Liliane C.D. (author)

Westgren, Magnus (author)

Bolte, Annemieke C. (author)

Papadogiannakis, Nikos (author)

Nasiell, Josefine (author)

show less...

(creator_code:org_t)

American Heart Association, 2008
2008
English.
In: Hypertension. - : American Heart Association. - 0194-911X .- 1524-4563. ; 51:5, s. 1295-1299

Related links:: https://www.ahajourn...; show more...; https://urn.kb.se/re...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

The aim of the present study was to evaluate the histopathology in placentas from patients with severe preeclampsia with and without hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. An additional aim was to compare the prevalence of infants born small for gestational age in the 2 groups. The study is retrospective and includes 178 women who have been diagnosed at the Karolinska University Hospital Huddinge or at the Free University Medical Center between 2000 and 2005 with severe preeclampsia. A total of 96 women had severe preeclampsia without signs of HELLP (preeclampsia group), whereas 82 fulfilled the criteria for having HELLP syndrome (HELLP group). Infarction (P=0.014), intervillous thrombosis (P<0.001), and abruption (P=0.002) were more common in the preeclampsia group than in the HELLP group. There was no statistically significant difference in the frequency of accelerated villous maturation (P=0.61), decidual arteriopathy (P=0.27), or chorioamnionitis (P=0.61). Furthermore, there was a higher mean placental weight, adjusted for gestational age, in the Swedish HELLP material than in the preeclampsia group (P<0.001). Finally, mothers in the preeclampsia group gave birth significantly more often to small for gestational age babies than mothers suffering from HELLP syndrome (P<0.001). The histopathologic profile and the range of placental lesions were partly different in the preeclampsia and HELLP patients. Considering the central role that placenta seems to have in preeclampsia, the present result might suggest that different underlying pathogenetic mechanisms and courses can be in play in patients with preeclampsia and HELLP syndrome.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)

Keyword

eclampsia
gestational hypertension
pregnancy hypertension
preeclampsia
pregnancy
proteinuria
women

Publication and Content Type

ref (subject category)
art (subject category)

Find in a library

Hypertension (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Vinnars, Marie-T ...; Wijnaendts, Lili ...; Westgren, Magnus; Bolte, Annemieke ...; Papadogiannakis, ...; Nasiell, Josefin ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Obstetrics Gynae ...

Articles in the publication: Hypertension

By the university: Umeå University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se