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Lumen apposing meta...
Lumen apposing metal stents vs double pigtail plastic stents for the drainage of pancreatic walled-off necrosis
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- Valente, Roberto (author)
- Umeå universitet,Kirurgi,Department of Surgery, Karolinska Institutet, Stockholm, Sweden; Department of Surgical Oncology, Anschutz Medical Campus, University of Colorado, Denver, CO, USA,Karolinska Inst, Dept Surg, Stockholm, Sweden.;Univ Colorado, Div Surg Oncol, Anschutz Med Campus, Denver, CO USA.;Umeå Univ Hosp, Dept Surg, Umeå, Sweden.;Karolinska Inst, Stockholm, Sweden.
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- Zarantonello, Laura (author)
- Uppsala universitet,Gastrointestinalkirurgi
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- Del Chiaro, Marco (author)
- Department of Surgical Oncology, Anschutz Medical Campus, University of Colorado, Denver, CO, USA,Univ Colorado, Div Surg Oncol, Anschutz Med Campus, Denver, CO USA.
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- Vujasinovic, Miroslav (author)
- Karolinska Institutet
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- Baldaque Silva, Francisco (author)
- Karolinska Institutet
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- Scandavini, Chiara M. (author)
- Umeå universitet,Kirurgi,Umeå Univ Hosp, Dept Surg, Umeå, Sweden.
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- Rangelova, Elena (author)
- Department of Surgery, Sahlgrenska Hospital, Gothenburg, Sweden,Sahlgrenska Hosp, Dept Surg, Gothenburg, Sweden.
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- Vespasiano, Francesca (author)
- Department of Upper Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden,Karolinska Univ Hosp, Dept Upper Digest Dis, Stockholm, Sweden.
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- Anzillotti, Giuseppe (author)
- Department of Upper Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden,Karolinska Univ Hosp, Dept Upper Digest Dis, Stockholm, Sweden.
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- Löhr, Johannes M. (author)
- Karolinska Institutet
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- Arnelo, Urban (author)
- Karolinska Institutet,Umeå universitet,Kirurgi,Department of Surgery, Karolinska Institutet, Stockholm, Sweden,Karolinska Inst, Dept Surg, Stockholm, Sweden.;Umeå Univ Hosp, Dept Surg, Umeå, Sweden.
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(creator_code:org_t)
- Edizioni Minerva Medica, 2024
- 2024
- English.
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In: Minerva gastroenterology. - : Edizioni Minerva Medica. - 2724-5365 .- 2724-5985. ; 70:1, s. 1-9
- Related links:
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https://doi.org/10.2...
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Abstract
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- BACKGROUND: Few studies compared lumen-apposing metal stents (LAMS) and standard double pigtail plastic stents (PS) for the endoscopic drainage of pancreatic walled-off necrosis (WON). Albeit sometimes large, previously described cohorts display considerable heterogeneity and often pooled together data from several centers, involving multiple operators and techniques. Moreover, they often lack a control group for the comparison of outcomes.AIM: to compare clinical efficacy and safety of PS versus LAMS for the endoscopic drainage of infected WON.METHODS: Single-centre, 1:1 case-control study. We compared patients undergoing endoscopic drainages of infected WON through LAMS (cases) or PS (controls). The primary endpoint was the clinical efficacy (resolution of the WON/sepsis), the secondary endpoint was safety (procedure-related complications).RESULTS: Thirty patients were enrolled between 2011 and 2017. Cases and controls were homogeneous in terms of etiology and clinical characteristics. 93% of cases and 86.7% of controls were clinically successfully treated, with no significant differences in rates of post-operative infections, bleedings and stent migrations (respectively 13.3% vs 21.4%; p=0.65; 13.3% vs 0%; p=0.48; 13.3% vs 7.1%; p=1.00). No difference was shown regarding the need for additional percutaneous or surgical treatments (33.3% vs 13.3%; p=0.39). Cases, however, displayed a significantly prolonged mean hospital stay (90.2 days vs 18.5 days; p<0.01) and a higher mean number of endoscopic procedures per patient (4.8 vs 1.5; p<0.01).CONCLUSIONS: PS might be not inferior to LAMS for the treatment WONs. Further prospective RCT is needed to compare clinical efficacy and safety in the two groups.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Keyword
- Acute pancreatitis
- Double pigtails plastic stents
- LAMS
- WON
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Valente, Roberto
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Zarantonello, La ...
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Del Chiaro, Marc ...
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Vujasinovic, Mir ...
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Baldaque Silva, ...
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Scandavini, Chia ...
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Rangelova, Elena
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Vespasiano, Fran ...
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Anzillotti, Gius ...
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Löhr, Johannes M ...
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Arnelo, Urban
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Gastroenterology ...
- Articles in the publication
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Minerva gastroen ...
- By the university
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Umeå University
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Uppsala University
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Karolinska Institutet