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Probiotics for the ...
Probiotics for the management of pediatric gastrointestinal disorders : position paper of the ESPGHAN special interest group on gut microbiota and modifications
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- Szajewska, Hania (author)
- From the Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland
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- Berni Canani, Roberto (author)
- Department of Translational Medical Science - Section of Paediatrics. University of Naples Federico II, Naples, Italy
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- Domellöf, Magnus, 1963- (author)
- Umeå universitet,Pediatrik
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- Guarino, Alfredo (author)
- Department of Translational Medical Science - Section of Paediatrics. University of Naples Federico II, Naples, Italy
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- Hojsak, Iva (author)
- the Children's Hospital Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia, University J.J. Strossmayer School of Medicine Osijek, Osijek, Croatia
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- Indrio, Flavia (author)
- Department of Medical and Surgical Science Pediatric Section, University of Foggia, Foggia, Italy
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- Lo Vecchio, Andrea (author)
- Department of Translational Medical Science - Section of Paediatrics. University of Naples Federico II, Naples, Italy
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- Mihatsch, Walter A. (author)
- Ulm University, Ulm, Germany
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- Mosca, Alexis (author)
- Department of Pediatric Gastroenterology and Nutrition, Hopital Robert Debré, Assistance Publique Hopitaux de Paris, Paris, France
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- Orel, Rok (author)
- Department of Gastroenterology, Hepatology and Nutrition, University Medical Centre Ljubljana, University Children's Hospital Ljubljana, Ljubljana, Slovenia
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- Salvatore, Silvia (author)
- Department of Pediatrics, "F. Del Ponte" Hospital, University of Insubria, Varese, Italy
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- Shamir, Raanan (author)
- Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel
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- van den Akker, Chris H P (author)
- University of Amsterdam and Vrije Universiteit Amsterdam, Emma Children's Hospital, Paediatrics - Neonatology, Amsterdam Reproduction & Development, Amsterdam, Netherlands
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- van Goudoever, Johannes B. (author)
- University of Amsterdam and Vrije Universiteit Amsterdam, Emma Children's Hospital, Paediatrics - Neonatology, Amsterdam Reproduction & Development, Amsterdam, Netherlands
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- Vandenplas, Yvan (author)
- UZ Brussel, Vrije Universiteit Brussel, the KidZ Health Castle, Brussels, Belgium
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- Weizman, Zvi (author)
- Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva, Israel
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From the Department of Paediatrics, Medical University of Warsaw, Warsaw, Poland Department of Translational Medical Science - Section of Paediatrics University of Naples Federico II, Naples, Italy (creator_code:org_t)
- Lippincott Williams & Wilkins, 2023
- 2023
- English.
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In: Journal of Pediatric Gastroenterology and Nutrition - JPGN. - : Lippincott Williams & Wilkins. - 0277-2116 .- 1536-4801. ; 76:2, s. 232-247
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- BACKGROUND: Probiotics, defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host, are widely used despite uncertainty regarding their efficacy and discordant recommendations about their use. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) Special Interest Group on Gut Microbiota and Modifications provides updated recommendations for the use of probiotics for the management of selected pediatric gastrointestinal disorders.METHODS: All systematic reviews and/or meta-analyses, as well as subsequently published randomized controlled trials (RCTs) (until December 2021), that compared the use of probiotics in all delivery vehicles and formulations, at any dose, with no probiotic (ie, placebo or no treatment), were eligible for inclusion. The recommendations were formulated only if at least 2 RCTs on a similar well-defined probiotic strain were available. The modified Delphi process was used to establish consensus on the recommendations.RESULTS: Recommendations for the use of specific probiotic strains were made for the management of acute gastroenteritis, prevention of antibiotic-associated diarrhea, nosocomial diarrhea and necrotizing enterocolitis, management of Helicobacter pylori infection, and management of functional abdominal pain disorders and infant colic.CONCLUSIONS: Despite evidence to support the use of specific probiotics in some clinical situations, further studies confirming the effect(s) and defining the type, dose, and timing of probiotics are still often required. The use of probiotics with no documented health benefits should be discouraged.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Szajewska, Hania
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Berni Canani, Ro ...
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Domellöf, Magnus ...
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Guarino, Alfredo
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Hojsak, Iva
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Indrio, Flavia
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Lo Vecchio, Andr ...
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Mihatsch, Walter ...
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Mosca, Alexis
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Orel, Rok
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Salvatore, Silvi ...
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Shamir, Raanan
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van den Akker, C ...
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van Goudoever, J ...
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Vandenplas, Yvan
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Weizman, Zvi
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Gastroenterology ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Pediatrics
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Umeå University