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Independent and inc...
Independent and incremental prognostic value of Doppler-derived left ventricular total isovolumic time in patients with systolic heart failure
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- Bajraktari, Gani (author)
- Service of Cardiology, Internal Medicine Clinic, University Clinical Centre of Kosova, Prishtina, Kosovo
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Dini, Frank Lloyd (author)
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Fontanive, Paolo (author)
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Elezi, Shpend (author)
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Berisha, Venera (author)
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Napoli, Anna Maria (author)
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Ciuti, Manrico (author)
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- Henein, Michael (author)
- Umeå universitet,Kardiologi,Heart centre
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(creator_code:org_t)
- Elsevier BV, 2011
- 2011
- English.
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In: International Journal of Cardiology. - : Elsevier BV. - 0167-5273 .- 1874-1754. ; 148:3, s. 271-275
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- BACKGROUND: A prolonged total isovolumic time (T-IVT) has been shown to be associated with worsening survival in patients submitted to coronary artery surgery. However, it is not known whether it has prognostic significance in patients with chronic systolic heart failure (HF).AIM: To determine the prognostic value of T-IVT in comparison with other clinical, biochemical and echocardiographic variables in patients with chronic systolic HF.METHODS: Patients (n=107; age 68+/-12years, 25% women) with chronic systolic HF, left ventricular ejection fraction (EF) <45%, and sinus rhythm, underwent a complete Doppler echocardiographic study, that included tissue Doppler long axis velocities and total isovolumic time (T-IVT), determined as [60-(total ejection time+total filling time)]. Plasma N-terminal pro-B natriuretic peptide (NT-pro-BNP) was also measured. The associations of dichotomous variables selected according to the Receiver Operator Characteristic analysis were assessed using the Cox proportional hazard model.RESULTS: Follow-up period was 37+/-18months. Multivariate predictors of events were T-IVT >/=12.3% s/min, mean E/E(m) ratio >/=10, log NT-pro-BNP levels >/=2.47pg/ml and LV EFCONCLUSIONS: Prolonged T-IVT added to the prognostic stratification of patients with systolic HF.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Heart failure
- doppler echocardiography
- left ventricular asynchrony
- left ventricular filling pressures
Publication and Content Type
- ref (subject category)
- art (subject category)
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