Adenovirus DNA in Guthrie cards from children who develop acute lymphoblastic leukaemia (ALL).

Talekar, G (author)

Huang, W (author)

Engvall, M (author)

Ornelles, D A (author)

Gooding, L R (author)

Gustafsson, B (author)

(creator_code:org_t)

2010-03-02
2010
English.
In: British Journal of Cancer. - : Springer Science and Business Media LLC. - 0007-0920 .- 1532-1827. ; 102:5, s. 796-8

Related links:: https://www.nature.c...; show more...; https://urn.kb.se/re...; https://doi.org/10.1...; http://kipublication...; show less...

Abstract Subject headings

BACKGROUND: In search of a proposed viral aetiology of childhood acute lymphoblastic leukaemia (ALL), the common species C adenoviruses were analysed in Guthrie cards. METHODS: Guthrie cards from 243 children who later developed ALL and from 486 matched controls were collected and analysed by nested polymerase chain reaction for the presence of adenovirus DNA. RESULTS: Adenovirus DNA was reliably detected from only two subjects, both of whom developed ALL. CONCLUSION: Adenovirus DNA is detected in Guthrie card samples at too low a frequency to reveal an association between adenovirus and the development of leukaemia.

By the author/editor: Honkaniemi, E; Talekar, G; Huang, W; Bogdanovic, G; Forestier, E; von Doblen, U; show more...; Engvall, M; Ornelles, D A; Gooding, L R; Gustafsson, B; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Pediatrics

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.