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Expression, purification, characterization, and in vivo targeting of trypanosome CTP synthetase for treatment of African sleeping sickness.
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- Fijolek, Artur (author)
- Umeå universitet,Institutionen för medicinsk kemi och biofysik
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- Hofer, Anders (author)
- Umeå universitet,Institutionen för medicinsk kemi och biofysik
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- Thelander, Lars (author)
- Umeå universitet,Institutionen för medicinsk kemi och biofysik
- (creator_code:org_t)
- 2007
- 2007
- English.
- In: Journal of biological chemistry. - 0021-9258. ; 282:16, s. 11858-11865
- Journal article (peer-reviewed)
Subject headings
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Keyword
- Animals
- Carbon-Nitrogen Ligases/*biosynthesis/*chemistry
- Cytidine/chemistry
- Cytosine/chemistry
- Dose-Response Relationship; Drug
- Enzyme Inhibitors/pharmacology
- Humans
- Kinetics
- Male
- Mice
- Mice; Inbred C57BL
- Trypanocidal Agents/pharmacology
- Trypanosoma brucei brucei/*enzymology
- Trypanosoma brucei gambiense/*enzymology
- Trypanosomiasis; African/*therapy
Publication and Content Type
- ref (subject category)
- art (subject category)
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