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n-3 Fatty acids are...
n-3 Fatty acids are positively associated with peak bone mineral density and bone accrual in healthy men : the NO2 Study
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- Högström, Magnus (författare)
- Umeå universitet,Idrottsmedicin
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- Nordström, Peter (författare)
- Umeå universitet,Idrottsmedicin,Institutionen för folkhälsa och klinisk medicin
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- Nordström, Anna (författare)
- Umeå universitet,Idrottsmedicin,Institutionen för samhällsmedicin och rehabilitering
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(creator_code:org_t)
- American Society for Clinical Nutrition, 2007
- 2007
- Engelska.
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Ingår i: American Journal of Clinical Nutrition. - : American Society for Clinical Nutrition. - 0002-9165 .- 1938-3207. ; 85:3, s. 803-807
- Relaterad länk:
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http://ajcn.nutritio...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background:Knowledge of the influence of nutritional intake on bone health is limited. Polyunsaturated fatty acids have been suggested to influence bone growth and modeling in humans, although data are sparse.Objective:The objective was to investigate the role of fatty acids in bone accumulation and the attainment of peak bone mass in young men.Design:The cohort studied consisted of 78 healthy young men with a mean age of 16.7 y at baseline. Bone mineral density (BMD; in g/cm2) of total body, hip, and spine was measured at baseline and at 22 and 24 y of age. Fatty acid concentrations were measured in the phospholipid fraction in serum at 22 y of age.Results:Concentrations of n−3 fatty acids were positively associated with total BMD (r = 0.27, P = 0.02) and spine BMD (r = 0.25, P = 0.02) at 22 y of age. A positive correlation between n−3 fatty acid concentrations and the changes in BMD at the spine (r = 0.26, P = 0.02) was found between 16 and 22 y of age. Concentrations of docosahexaenoic acid (DHA, 22:6n−3) were positively associated with total BMD (r = 0.32, P = 0.004) and BMD at the spine (r = 0.30, P = 0.008) at 22 y of age. A positive correlation was also found between DHA concentrations and the changes in BMD at the spine (r = 0.26, P = 0.02) between 16 and 22 y of age.Conclusion:The results showed that n−3 fatty acids, especially DHA, are positively associated with bone mineral accrual and, thus, with peak BMD in young men.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences (hsv//eng)
Nyckelord
- Administration
- Oral
- Adolescent
- Bone Density/drug effects
- Bone and Bones/drug effects/*physiology
- Cohort Studies
- Diet
- Exercise
- Fatty Acids/blood
- Fatty Acids; Omega-3/administration & dosage/*pharmacology
- Follow-Up Studies
- Humans
- Male
- Phospholipids/*blood
- Reference Values
- Time Factors
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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