Sökning: id:"swepub:oai:DiVA.org:uu-104372" > Mechanism of TGF-be...
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000 | 02462naa a2200337 4500 | |
001 | oai:DiVA.org:uu-104372 | |
003 | SwePub | |
008 | 090528s2009 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:umu-36337 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1043722 URI |
024 | 7 | a https://doi.org/10.1016/j.ceb.2009.01.0212 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-363372 URI |
040 | a (SwePub)uud (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a for2 swepub-publicationtype |
100 | 1 | a Heldin, Carl-Henriku Uppsala universitet,Ludwiginstitutet för cancerforskning4 aut0 (Swepub:uu)carlheld |
245 | 1 0 | a Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition |
264 | 1 | b Elsevier Ltd.c 2009 |
338 | a print2 rdacarrier | |
520 | a Members of the transforming growth factor-beta (TGF-beta) family have important roles during embryogenesis, as well as in the control of tissue homeostasis in the adult. They exert their cellular effects via binding to serine/threonine kinase receptors. Members of the Smad family of transcription factors are important intracellular messengers, and recent studies have shown that the ubiquitin ligase TRAF6 mediates other specific signals. TGF-beta signaling is tightly controlled by post-translational modifications, which regulate the activity, stability, and subcellular localization of the signaling components. The aim of this review is to summarize some of the recent findings on the mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition. | |
653 | a MEDICINE | |
653 | a MEDICIN | |
700 | 1 | a Landström, Maréneu Uppsala universitet,Ludwiginstitutet för cancerforskning,Institutionen för genetik och patologi,Ludwig Institute for Cancer Research, Uppsala University4 aut0 (Swepub:umu)mala0231 |
700 | 1 | a Moustakas, Aristidisu Uppsala universitet,Ludwiginstitutet för cancerforskning4 aut0 (Swepub:uu)arimo287 |
710 | 2 | a Uppsala universitetb Ludwiginstitutet för cancerforskning4 org |
773 | 0 | t Current Opinion in Cell Biologyd : Elsevier Ltd.g 21:2, s. 166-176q 21:2<166-176x 0955-0674x 1879-0410 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-104372 |
856 | 4 8 | u https://doi.org/10.1016/j.ceb.2009.01.021 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-36337 |
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