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Prescription and transcription errors in multidose-dispensed medications on discharge from hospital : an observationaland interventional study

Alassaad, Anna (author)
Uppsala universitet,Klinisk farmakogenomik och osteoporos
Gillespie, Ulrika (author)
Uppsala universitet,Avdelningen för farmakokinetik och läkemedelsterapi,PKPD
Bertilsson, Maria (author)
Uppsala universitet,Uppsala kliniska forskningscentrum (UCR)
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Melhus, Håkan (author)
Uppsala universitet,Klinisk farmakogenomik och osteoporos
Hammarlund-Udenaes, Margareta (author)
Uppsala universitet,Avdelningen för farmakokinetik och läkemedelsterapi,Translational PKPD
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 (creator_code:org_t)
2011-12-29
2013
English.
In: Journal of Evaluation In Clinical Practice. - : Wiley. - 1356-1294 .- 1365-2753. ; 19:1, s. 185-191
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Background Medication errors frequently occur when patients are transferred between health care settings. The main objective of this study was to investigate the frequency, type and severity of prescribing and transcribing errors for drugs dispensed in multidose plastic packs when patients are discharged from the hospital. The secondary objective was to correct identified errors and suggest measures to promote safe prescribing.Methods The drugs on the patients' multidose drug dispensing (MDD) order sheets and the medication administration records were reconciled prior to the MDD orders being sent to the pharmacy for dispensing. Discrepancies were recorded and the prescribing physician was notified and given the opportunity to change the order. Discrepancies categorized as unintentional and related to the discharge process were subject to further analysis.Results Seventy-two (25%) of the 290 reviewed MDD orders had at least one discharge error. In total, 120 discharge errors were identified, of which 49 (41%) were assessed as being of moderate and three (3%) of major severity. Orders with a higher number of medications and orders from the orthopaedic wards had a significantly higher error rate.Conclusion The main purpose of the MDD system is to increase patient safety by reducing medication errors. However, this study shows that prescribing and transcribing errors frequently occur when patients are hospitalized. Because the population enrolled in the MDD system is an elderly, physically vulnerable group with a high number of prescribed drugs, preventive measures to ensure safe prescribing of MDD drugs are warranted.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)

Keyword

medication error
medication reconciliation
multi-dose dispensed medications
patient safety
prescription error
transition of care
Pharmaceutical Science
Farmaceutisk vetenskap
Pharmacokinetics and Drug Therapy
Farmakokinetik och läkemedelsterapi

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ref (subject category)
art (subject category)

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Alassaad, Anna
Gillespie, Ulrik ...
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Melhus, Håkan
Hammarlund-Udena ...
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MEDICAL AND HEALTH SCIENCES
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