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Exercise test using...
Exercise test using dry air in random adolescents: temporal profile and predictors of bronchoconstriction
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- Johansson, Henrik, 1965- (author)
- Uppsala universitet,Fysioterapi,Lungmedicin och allergologi
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- Norlander, Katarina (author)
- Uppsala universitet,Öron-, näs- och halssjukdomar
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- Alving, Kjell (author)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa
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- Hedenström, Hans (author)
- Uppsala universitet,Klinisk fysiologi
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- Janson, Christer (author)
- Uppsala universitet,Lungmedicin och allergologi
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- Malinovschi, Andrei (author)
- Uppsala universitet,Klinisk fysiologi
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- Nordang, Leif (author)
- Uppsala universitet,Öron-, näs- och halssjukdomar
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- Emtner, Margareta (author)
- Uppsala universitet,Fysioterapi,Lungmedicin och allergologi
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(creator_code:org_t)
- 2015-11-20
- 2016
- English.
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In: Respirology (Carlton South. Print). - : Wiley. - 1323-7799 .- 1440-1843. ; 21:2, s. 289-296
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Background and objectiveGuidelines recommend exercise tests using dry air to diagnose exercise-induced bronchoconstriction (EIB). Lung function changes subsequent to these tests have not been investigated in a general adolescent population, and it remains unknown whether signs of airway inflammation, measured using exhaled nitric oxide (FeNO), can predict a positive response. The aim of this study was to investigate the temporal aspect of decline in forced expiratory volume in 1 s (FEV1) after an exercise test using dry air, and to investigate predictors of EIB.MethodsFrom a cross-sectional study on adolescents aged 13–15 years (n = 3838), a random subsample of 146 adolescents (99 with and 47 without self-reported exercise-induced dyspnoea) underwent standardized treadmill exercise tests for EIB while breathing dry air.ResultsOf the adolescents, 34% had a positive EIB test (decline of ≥10% in FEV1 from baseline) within 30 min. Of the subjects with EIB, 53% showed the greatest decline in FEV1 at 5 to 10 min (mean decline 18.5%), and the remaining 47% of the subjects showed the greatest decline at 15 to 30 min (mean decline 18.9%) after exercise. Increased FeNO (>20 ppb), female gender and self-reported exercise-induced dyspnoea were independently associated with a positive EIB test.ConclusionWhen assessing general adolescents for EIB with exercise test using dry air, there is a temporal variation in the greatest FEV1 decline after exercise. Therefore, lung function should be measured for at least 30 min after the exercise. Increased FeNO, female gender and self-reported exercise-induced dyspnoea can be predictors of a positive EIB test.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Keyword
- adolescents
- dry air
- exercise induced bronchoconstriction test
- exhaled nitric oxide
- general population
Publication and Content Type
- ref (subject category)
- art (subject category)
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